International
Cancer drug cooperation could save 1.5 mn lives a year: researchers
AFP
Around 1.5 million lives could be saved every year if the world worked together to more swiftly approve new cancer drugs, researchers said Tuesday.
The figure was based on how long it took two recent cancer drugs to be approved across the world after they were given the green light by the United States.
Pembrolizumab, an effective treatment for most lung cancers, was approved by the US Food and Drug Administration (FDA) in 2016.
More than 600,000 years of patients’ lives could have been saved if Brazil, Canada, China, India, Japan and the European Union had approved the drug at the same time, according to an analysis published in the Harvard Business Review, which is not peer-reviewed.
The authors, including US oncologist Bobby Daly, also looked at enzalutamide, which is used to treat prostate cancer.
Enzalutamide was approved by the FDA in 2012, but was not authorised in China for another seven years, partly due to a requirement for separate trials to be carried out there.
The analysis by members of the Bloomberg New Economy International Cancer Coalition found that 284,000 years of patient lives could have been saved if other countries had approved the drug alongside the FDA.
Extrapolating out from their findings, the researchers estimated that if each of the approximately seven cancer drugs approved by the FDA a year were authorised worldwide, it would reduce the number of cancer-related deaths by 10-20 percent.
That represents roughly 1.5 million of the around 10 million people who die of cancer every year.
‘Challenging’ for doctors
“In China alone an estimated 500,000 patient life-years could be saved through harmonisation of trial requirements that have delayed patient access to treatment,” former Australian prime minister Kevin Rudd, co-chair of the Bloomberg cancer coalition, said in a statement.
Mary Gospodarowicz, also a member of the coalition, said that it was “challenging” as an oncologist in Canada when a drug was approved in the US but would take years to be able to prescribe it to her patients.
The study assumed that the rest of the world had the infrastructure to diagnose and treat cancer as well as the US, which is not always the case, Gospodarowicz told AFP via phone from the World Cancer Congress in Geneva on Tuesday.
But it served as an example of how “removing the barriers to drug approval would be beneficial to patients around the world,” said the former president of the Union for International Cancer Control, which is holding the congress.
The authors of the analysis called on countries to embrace Project Orbis, a US-led framework aiming to get cancer drugs trialled and approved at the same time in multiple countries.
“The US has already made significant progress in setting up the regulatory infrastructure for cancer treatment with the Project Orbis initiative and the task ahead is to take that framework and internationalise it,” former New York mayor Michael Bloomberg said in a statement.
International
Dominican court postpones hearing in deadly nightclub collapse case
A Dominican court on Monday postponed until March a preliminary hearing against the owners of a nightclub that collapsed last year, killing more than 200 people.
The roof of the Jet Set nightclub collapsed in the early hours of April 8, 2025, during a concert by popular merengue singer Rubby Pérez, who died along with 235 other people.
Jet Set owner and manager Antonio Espaillat and his sister Maribel, who served as the club’s administrator, were arrested on charges of involuntary manslaughter but were later released on bail after posting approximately $842,500.
Both appeared at the Palace of Justice, where they were met by a small protest from relatives and friends of the victims.
“Thirty years in prison is not enough” and “President, we want JUSTICE,” read signs held by demonstrators.
The preliminary hearing determines whether there is sufficient evidence to send the case to trial. The court decided to reschedule the hearing for March 16.
“We don’t want money and we’re not demanding anything else, only justice for those who died,” said Secundino Pérez, a 75-year-old shopkeeper who lost 12 friends in the Jet Set tragedy.
“Antonio and his family celebrated Christmas sitting at a table, celebrating their freedom,” said Edgar Gómez, who lost his daughter in the collapse.
The Dominican Republic’s Public Prosecutor’s Office maintains that the defendants “significantly altered” the structure of the nightclub. Prosecutors filed formal charges in November and requested that the case proceed to trial.
The charge of involuntary manslaughter carries a sentence of three months to two years in prison.
“May your conscience never let you sleep. I lost my son,” a woman shouted through tears before the hearing, while others chanted, “Murderers, murderers, murderers.”
International
Venezuelan opposition leader dedicates Nobel Prize to Trump
U.S. President Donald Trump said last week that he was “eager” to welcome the opposition leader, who left Venezuela clandestinely with U.S. assistance, to receive her Nobel Prize in Oslo.
Machado dedicated her Nobel Prize to Trump, who nevertheless showed a very cautious attitude toward including her in any potential political transition in Venezuela.
The opposition leader said on Monday, after an audience with Pope Leo XIV, that “the defeat of evil is closer” in Venezuela following the U.S. military operation that overthrew and removed President Nicolás Maduro and his wife from the country.
Trump has claimed that he is now in control of the South American nation, stating that the primary objective at this stage is to stabilize the country before considering elections.
Venezuelan oil is Washington’s main objective, Trump added after Maduro’s overthrow.
International
Police hunt gunmen after fatal shooting in Corsica
A man was shot dead on the French Mediterranean island of Corsica, local media reported. The victim was identified as Alain Orsoni, former president of local football club AC Ajaccio, according to sources close to the investigation cited by French news channel BFMTV.
Orsoni, 71, was killed in the town of Vero, near Ajaccio, the island’s capital, while attending his mother’s funeral.
He was also a former member of the National Liberation Front of Corsica (FLNC), a nationalist organization that has long sought independence for the island, reports said.
BFMTV reported that the gunmen fled the scene and remain at large. Local police have opened an investigation into the shooting.
Dominican court postpones hearing in deadly nightclub collapse case
Venezuelan opposition leader dedicates Nobel Prize to Trump
Police hunt gunmen after fatal shooting in Corsica
Tec de Monterrey honors one of its students for his contribution to nanotechnology in medicine
Defense Minister commends salvadoran soldier for Central American Cross Country victory
Extension of the state of emergency approved in southern Chile
-
International5 days agoPetro and Trump Agree on Joint Action Against ELN Guerrillas After Tense Diplomacy
-
International5 days agoTrump Signals Extended U.S. Influence Over Venezuela Following Military Operation
-
International3 days agoU.S. strike in Caracas killed 32 cuban security officers, experts say surprise was crucial
-
International5 days agoSenate Bipartisan Vote Moves Measure to Block Further U.S. Military Action in Venezuela
-
International4 days agoOne Dead and Nine Injured After Explosion in Southwest Madrid
-
International2 days ago
U.S. Issues Urgent Evacuation Call for Citizens in Venezuela
-
International5 days agoLula Vetoes Bill That Would Have Shortened Bolsonaro’s Prison Sentence
-
International4 days agoPope Leo XIV warns of rising “war enthusiasm” in global politics
-
International4 days agoReport: Vatican mediation included russian asylum offer ahead of Maduro’s capture
-
Central America3 hours agoU.S. and El Salvador maintain close partnership, embassy says
-
International3 hours agoDeadly van accident near Brazil border leaves 11 dead in Bolivia
-
Central America3 hours agoTaiwan’s $10 million donation after 2001 earthquakes allegedly diverted in El Salvador
-
International3 hours agoDominican court postpones hearing in deadly nightclub collapse case
-
International3 hours agoPolice hunt gunmen after fatal shooting in Corsica
-
International3 hours agoU.S. to host Danish and Greenlandic Foreign Ministers at the White House
-
International3 hours agoVenezuelan opposition leader dedicates Nobel Prize to Trump
-
International3 hours agoEx-President accused of bid to establish dictatorship as verdict nears in South Korea