International
Cancer drug cooperation could save 1.5 mn lives a year: researchers
AFP
Around 1.5 million lives could be saved every year if the world worked together to more swiftly approve new cancer drugs, researchers said Tuesday.
The figure was based on how long it took two recent cancer drugs to be approved across the world after they were given the green light by the United States.
Pembrolizumab, an effective treatment for most lung cancers, was approved by the US Food and Drug Administration (FDA) in 2016.
More than 600,000 years of patients’ lives could have been saved if Brazil, Canada, China, India, Japan and the European Union had approved the drug at the same time, according to an analysis published in the Harvard Business Review, which is not peer-reviewed.
The authors, including US oncologist Bobby Daly, also looked at enzalutamide, which is used to treat prostate cancer.
Enzalutamide was approved by the FDA in 2012, but was not authorised in China for another seven years, partly due to a requirement for separate trials to be carried out there.
The analysis by members of the Bloomberg New Economy International Cancer Coalition found that 284,000 years of patient lives could have been saved if other countries had approved the drug alongside the FDA.
Extrapolating out from their findings, the researchers estimated that if each of the approximately seven cancer drugs approved by the FDA a year were authorised worldwide, it would reduce the number of cancer-related deaths by 10-20 percent.
That represents roughly 1.5 million of the around 10 million people who die of cancer every year.
‘Challenging’ for doctors
“In China alone an estimated 500,000 patient life-years could be saved through harmonisation of trial requirements that have delayed patient access to treatment,” former Australian prime minister Kevin Rudd, co-chair of the Bloomberg cancer coalition, said in a statement.
Mary Gospodarowicz, also a member of the coalition, said that it was “challenging” as an oncologist in Canada when a drug was approved in the US but would take years to be able to prescribe it to her patients.
The study assumed that the rest of the world had the infrastructure to diagnose and treat cancer as well as the US, which is not always the case, Gospodarowicz told AFP via phone from the World Cancer Congress in Geneva on Tuesday.
But it served as an example of how “removing the barriers to drug approval would be beneficial to patients around the world,” said the former president of the Union for International Cancer Control, which is holding the congress.
The authors of the analysis called on countries to embrace Project Orbis, a US-led framework aiming to get cancer drugs trialled and approved at the same time in multiple countries.
“The US has already made significant progress in setting up the regulatory infrastructure for cancer treatment with the Project Orbis initiative and the task ahead is to take that framework and internationalise it,” former New York mayor Michael Bloomberg said in a statement.
International
Trump administration launches large-scale immigration operation in Chicago
The administration of U.S. President Donald Trump intensified a large-scale immigration operation in the Chicago area with the arrival of additional Border Patrol agents on Tuesday and the presence of Department of Homeland Security (DHS) Secretary Kristi Noem during a raid.
Noem posted a video on her X account showing the immigration operation, in which DHS reportedly removed “violent criminals” from the streets. The footage shows Noem observing the arrest of a man taken into custody at his home early Tuesday morning at an undisclosed location.
“I was in Chicago today to make it clear that we will not back down,” the secretary wrote. “Our work is just beginning,” she added.
The warning from Noem was echoed by U.S. Customs and Border Protection (CBP) Chief Gregory Bovino, who posted a video on X Tuesday showing multiple Border Patrol vehicles arriving in the city with the caption: “Chicago, we are here!”
Bovino, who led the immigration crackdown in Los Angeles implemented since last June, said the team will remain in Chicago to continue the mission they started in California.
Operation “Midway Blitz” is currently focused on the Chicago metropolitan area and its suburbs. Activists and residents have reported sightings of masked agents and unmarked vehicles in predominantly Latino neighborhoods.
International
Asteroid 2025 FA22, 300 meters long, to pass safely near Earth tomorrow
An asteroid nearly 300 meters long—about a thousand times larger than the meteor that struck the Russian city of Chelyabinsk in 2013—will pass close to Earth tomorrow, Thursday, the Solar Astronomy Laboratory of the Russian Academy of Sciences reported today.
“One of the largest asteroids of the year, 2025 FA22, will pass at a distance slightly greater than the diameter of the Moon’s orbit, reaching its closest approach to Earth around 10:00 a.m. Moscow time (1:00 a.m. in El Salvador),” the research center stated on its official website.
According to Russian astronomers, the asteroid has an average width of about 166 meters and a total length of 290 meters. “Its mass is approximately a thousand times greater than that of the Chelyabinsk meteor,” they added.
Despite its significant size, the laboratory emphasized that “the probability of this object striking the planet is extremely low,” describing the risk as “negligible.” “If its current trajectory holds, it will safely bypass both Earth and the Moon,” the scientists assured.
International
Trump: U.S. has hit three venezuelan narco boats in Caribbean
U.S. President Donald Trump said Tuesday that American forces have struck three suspected Venezuelan drug-trafficking vessels in the Caribbean so far, not two as previously reported.
“We took down boats. It was actually three boats, not two, but you only saw two,” Trump told reporters at the White House before departing for a state visit to the United Kingdom.
The president was asked about remarks by Venezuelan leader Nicolás Maduro, who accused Washington of plotting to invade his country.
“Stop sending members of the Tren de Aragua to the United States. Stop sending drugs to the United States,” Trump responded.
The Republican leader mentioned this third vessel a day after announcing that U.S. forces had struck a speedboat in which, according to him, three “terrorists” were killed. Later, from the Oval Office, he claimed the boat had been carrying cocaine and fentanyl.
The attacks come amid escalating tensions between Washington and Caracas, as the U.S. military maintains a Caribbean deployment under the banner of counter-narcotics operations.
The Trump administration accuses Maduro of heading the so-called Cartel of the Suns, which the Venezuelan government denies. Washington has also offered a $50 million reward for information leading to Maduro’s capture.
On Monday, Maduro said communications with the U.S. were “broken” in the face of what he called an “aggression” and declared that Venezuela is now “better prepared” in case of an “armed struggle.”
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