International
Cancer drug cooperation could save 1.5 mn lives a year: researchers
AFP
Around 1.5 million lives could be saved every year if the world worked together to more swiftly approve new cancer drugs, researchers said Tuesday.
The figure was based on how long it took two recent cancer drugs to be approved across the world after they were given the green light by the United States.
Pembrolizumab, an effective treatment for most lung cancers, was approved by the US Food and Drug Administration (FDA) in 2016.
More than 600,000 years of patients’ lives could have been saved if Brazil, Canada, China, India, Japan and the European Union had approved the drug at the same time, according to an analysis published in the Harvard Business Review, which is not peer-reviewed.
The authors, including US oncologist Bobby Daly, also looked at enzalutamide, which is used to treat prostate cancer.
Enzalutamide was approved by the FDA in 2012, but was not authorised in China for another seven years, partly due to a requirement for separate trials to be carried out there.
The analysis by members of the Bloomberg New Economy International Cancer Coalition found that 284,000 years of patient lives could have been saved if other countries had approved the drug alongside the FDA.
Extrapolating out from their findings, the researchers estimated that if each of the approximately seven cancer drugs approved by the FDA a year were authorised worldwide, it would reduce the number of cancer-related deaths by 10-20 percent.
That represents roughly 1.5 million of the around 10 million people who die of cancer every year.
‘Challenging’ for doctors
“In China alone an estimated 500,000 patient life-years could be saved through harmonisation of trial requirements that have delayed patient access to treatment,” former Australian prime minister Kevin Rudd, co-chair of the Bloomberg cancer coalition, said in a statement.
Mary Gospodarowicz, also a member of the coalition, said that it was “challenging” as an oncologist in Canada when a drug was approved in the US but would take years to be able to prescribe it to her patients.
The study assumed that the rest of the world had the infrastructure to diagnose and treat cancer as well as the US, which is not always the case, Gospodarowicz told AFP via phone from the World Cancer Congress in Geneva on Tuesday.
But it served as an example of how “removing the barriers to drug approval would be beneficial to patients around the world,” said the former president of the Union for International Cancer Control, which is holding the congress.
The authors of the analysis called on countries to embrace Project Orbis, a US-led framework aiming to get cancer drugs trialled and approved at the same time in multiple countries.
“The US has already made significant progress in setting up the regulatory infrastructure for cancer treatment with the Project Orbis initiative and the task ahead is to take that framework and internationalise it,” former New York mayor Michael Bloomberg said in a statement.
International
Paraguay launches dengue vaccination for children in high-risk areas
Dengue fever, transmitted by the Aedes aegypti mosquito, remains a persistent threat in tropical and subtropical countries such as Paraguay, where it claimed the lives of 132 people among nearly 100,000 infections during the 2023–2024 Southern Hemisphere summer, according to official data. However, that figure was lower than the record set in the 2012–2013 season, when 252 deaths were reported among roughly 130,000 infections.
“Today marks a very important step toward protecting our children and bringing peace of mind to families,” Paraguay’s Minister of Health, María Teresa Barán Wasilchuk, said in a speech on Wednesday.
The vaccine will be administered to children between 6 and 8 years old in municipalities with the highest incidence of dengue cases in the past five years. Authorities will use TAK-003 (Qdenga), developed by Takeda—one of Japan’s largest pharmaceutical companies—which was approved by the World Health Organization (WHO) in 2024.
“We celebrate this step, which positions Paraguay as a country with one of the most robust immunization programs,” said Héctor Castro, director of the Acosta Ñu Pediatric Hospital. “We will work tirelessly to ensure this government decision becomes a success in the fight against this scourge.”
Vaccinating children against dengue “is not only a historic and public health milestone, but also a humanitarian one,” Castro added during remarks delivered at the hospital in San Lorenzo, near the capital, Asunción.
International
President Paz dismisses Vidovic Over 2015 corruption sentence
Justice Minister Freddy Vidovic took office on November 9 after taking the oath of peace for a five-year term. However, his tenure was short-lived: he was removed from the position on Thursday after a past criminal conviction came to light.
In 2015, Vidovic was sentenced to three years in prison for bribery in favor of Peruvian businessman Martín Belaúnde, a former adviser to ex-president Ollanta Humala. Belaúnde was captured in Bolivia ten years ago and handed over to Peruvian authorities, who sought him for alleged involvement in a corruption case that also implicated Humala, who later served time for corruption charges.
At the time, Vidovic was part of Belaúnde’s legal defense team. He was accused of assisting the former presidential adviser in a failed attempt to escape while in Bolivia.
Following the revelation of the conviction, President Paz dismissed Vidovic and appointed Jorge Franz García as the new Justice Minister, according to the decree published on Thursday.
On Wednesday night, Government Minister Marco Antonio Oviedo confirmed the three-year sentence against Vidovic, noting that this background meant he “could not hold public office.”
Before his dismissal was made public, Vidovic acknowledged on his Facebook account that he had been convicted, but claimed he had been a victim of “kidnapping and torture” and argued that the ruling was “invalid and tainted.”
International
International organizations push for expanded kidney transplant access in SICA region
A group of international organizations held a high-level meeting in Antigua Guatemala, Guatemala, to address transplantation as a key component in the comprehensive management of Chronic Kidney Disease (CKD) in the countries of the Central American Integration System (SICA).
The meeting was organized by Spain’s National Transplant Organization (ONT), the Pan American Health Organization (PAHO), and the Executive Secretariat of the Council of Ministers of Health of Central America and the Dominican Republic (SECOMISCA). It was conducted within the framework of the Triangular Cooperation Program of the Spanish Agency for International Development Cooperation (AECID) and endorsed by the Ibero-American Donation and Transplant Network/Council (RCIDT).
The purpose of the gathering was to promote kidney transplantation as a priority option for renal replacement therapy, given its superior cost-effectiveness and health outcomes compared with dialysis.
According to a joint press release, the participating organizations also sought to encourage political commitment to advance equitable access to kidney transplantation and to identify common priorities for regional cooperation.
During the event, institutions presented the current status of Chronic Kidney Disease (CKD) and access to kidney transplantation in SICA countries, as well as the 2019–2030 Regional Donation and Transplant Strategy (CD 57R11). The meeting also facilitated a regional political dialogue aimed at incorporating transplantation into the comprehensive management of CKD, with the goal of generating recommendations to ensure equitable and progressive access to renal replacement therapies.
Additionally, the organizations explored opportunities to improve CKD registry systems, including transplantation data.
The meeting was convened in response to the growing burden of Chronic Kidney Disease across the World Health Organization (WHO) regions.
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