International
Cancer drug cooperation could save 1.5 mn lives a year: researchers
AFP
Around 1.5 million lives could be saved every year if the world worked together to more swiftly approve new cancer drugs, researchers said Tuesday.
The figure was based on how long it took two recent cancer drugs to be approved across the world after they were given the green light by the United States.
Pembrolizumab, an effective treatment for most lung cancers, was approved by the US Food and Drug Administration (FDA) in 2016.
More than 600,000 years of patients’ lives could have been saved if Brazil, Canada, China, India, Japan and the European Union had approved the drug at the same time, according to an analysis published in the Harvard Business Review, which is not peer-reviewed.
The authors, including US oncologist Bobby Daly, also looked at enzalutamide, which is used to treat prostate cancer.
Enzalutamide was approved by the FDA in 2012, but was not authorised in China for another seven years, partly due to a requirement for separate trials to be carried out there.
The analysis by members of the Bloomberg New Economy International Cancer Coalition found that 284,000 years of patient lives could have been saved if other countries had approved the drug alongside the FDA.
Extrapolating out from their findings, the researchers estimated that if each of the approximately seven cancer drugs approved by the FDA a year were authorised worldwide, it would reduce the number of cancer-related deaths by 10-20 percent.
That represents roughly 1.5 million of the around 10 million people who die of cancer every year.
‘Challenging’ for doctors
“In China alone an estimated 500,000 patient life-years could be saved through harmonisation of trial requirements that have delayed patient access to treatment,” former Australian prime minister Kevin Rudd, co-chair of the Bloomberg cancer coalition, said in a statement.
Mary Gospodarowicz, also a member of the coalition, said that it was “challenging” as an oncologist in Canada when a drug was approved in the US but would take years to be able to prescribe it to her patients.
The study assumed that the rest of the world had the infrastructure to diagnose and treat cancer as well as the US, which is not always the case, Gospodarowicz told AFP via phone from the World Cancer Congress in Geneva on Tuesday.
But it served as an example of how “removing the barriers to drug approval would be beneficial to patients around the world,” said the former president of the Union for International Cancer Control, which is holding the congress.
The authors of the analysis called on countries to embrace Project Orbis, a US-led framework aiming to get cancer drugs trialled and approved at the same time in multiple countries.
“The US has already made significant progress in setting up the regulatory infrastructure for cancer treatment with the Project Orbis initiative and the task ahead is to take that framework and internationalise it,” former New York mayor Michael Bloomberg said in a statement.
International
Mexico, Brazil and Colombia left out of Trump’s “Shield of the Americas” summit
Left-wing governments in Latin America, including Mexico, Brazil and Colombia, were excluded from the “Shield of the Americas” summit convened by U.S. President Donald Trump.
The meeting, held in Miami, Florida, brought together 12 presidents from across the continent to discuss strategies to combat drug cartels and organized crime.
In Mexico’s case, President Claudia Sheinbaum had recently rejected the use of military force as a solution to the drug trafficking problem. She has argued that her administration’s security strategy is producing results and emphasized that force alone is not the answer.
During the summit, Trump said that most narcotics entering the United States come through Mexico and referred to his previous conversations with Sheinbaum on the issue.
“I like the president very much, she’s a very good person,” Trump said. “But I told her: ‘Let me eradicate the cartels.’ And she said, ‘No, no, no, please, president.’ We have to eradicate them. We have to finish them.”
The remarks highlighted ongoing differences between Washington and Mexico over how to confront drug trafficking networks operating across the region.
International
Trump announces 17-nation alliance in the Americas to “destroy” drug cartels
U.S. President Donald Trump announced on Saturday the creation of a 17-nation alliance across the Americas aimed at dismantling drug cartels, during a regional summit held at his golf club in Doral.
Speaking to a group of allied leaders at the Shield of the Americas Summit, Trump said the initiative would rely on military force to eliminate powerful criminal networks operating throughout the hemisphere.
“The heart of our agreement is the commitment to use lethal military force to destroy these sinister cartels and terrorist networks. Once and for all, we will put an end to them,” Trump told the assembled heads of state.
The Republican leader argued that large portions of territory in the Western Hemisphere have fallen under the control of transnational gangs and pledged U.S. support to governments seeking to confront them. He even suggested the potential use of highly precise missiles against cartel leaders.
Before making the announcement, Trump greeted the roughly twelve leaders attending the summit, including close allies such as Javier Milei, Daniel Noboa and Nayib Bukele, whom he described as a “great president.”
The meeting forms part of Trump’s broader regional strategy inspired by his reinterpretation of the Monroe Doctrine, which seeks to reinforce Washington’s influence in the Americas, strengthen security cooperation and counter the growing presence of powers such as China.
Trump pointed to recent U.S. actions in the region as examples of his administration’s approach, including the operation that led to the capture of former Venezuelan president Nicolás Maduro earlier this year.
The summit also takes place amid escalating international tensions following the conflict launched last week by the United States and Israel against Iran.
International
Trump replaces Homeland Security Secretary Kristi Noem with Senator Markwayne Mullin
U.S. President Donald Trump announced Thursday the departure of Kristi Noem as Secretary of Homeland Security, one of the key architects of the administration’s policy of deporting undocumented immigrants.
Noem, who has been assigned a new role as a “special envoy” to Latin America, will be replaced starting March 31 by Republican Senator Markwayne Mullin, the president said in a message posted on his social media platform Truth Social.
According to media reports, Trump made the decision after Noem’s recent hearings in Congress, during which she faced tough questions regarding the awarding of a major public contract.
Mexico, Brazil and Colombia left out of Trump’s “Shield of the Americas” summit
Trump announces 17-nation alliance in the Americas to “destroy” drug cartels
Trump replaces Homeland Security Secretary Kristi Noem with Senator Markwayne Mullin
Tec de Monterrey honors one of its students for his contribution to nanotechnology in medicine
Defense Minister commends salvadoran soldier for Central American Cross Country victory
Extension of the state of emergency approved in southern Chile
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International3 days agoTrump announces 17-nation alliance in the Americas to “destroy” drug cartels
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International4 days agoYoung Woman Will Represent Mexico at 2026 World Cup Opener, Says President Sheinbaum
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International2 days ago
Mexico, Brazil and Colombia left out of Trump’s “Shield of the Americas” summit
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International4 days agoTrump replaces Homeland Security Secretary Kristi Noem with Senator Markwayne Mullin