International

Cancer drug cooperation could save 1.5 mn lives a year: researchers

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AFP

Around 1.5 million lives could be saved every year if the world worked together to more swiftly approve new cancer drugs, researchers said Tuesday.

The figure was based on how long it took two recent cancer drugs to be approved across the world after they were given the green light by the United States.

Pembrolizumab, an effective treatment for most lung cancers, was approved by the US Food and Drug Administration (FDA) in 2016.

More than 600,000 years of patients’ lives could have been saved if Brazil, Canada, China, India, Japan and the European Union had approved the drug at the same time, according to an analysis published in the Harvard Business Review, which is not peer-reviewed.

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The authors, including US oncologist Bobby Daly, also looked at enzalutamide, which is used to treat prostate cancer.

Enzalutamide was approved by the FDA in 2012, but was not authorised in China for another seven years, partly due to a requirement for separate trials to be carried out there.

The analysis by members of the Bloomberg New Economy International Cancer Coalition found that 284,000 years of patient lives could have been saved if other countries had approved the drug alongside the FDA.

Extrapolating out from their findings, the researchers estimated that if each of the approximately seven cancer drugs approved by the FDA a year were authorised worldwide, it would reduce the number of cancer-related deaths by 10-20 percent.

That represents roughly 1.5 million of the around 10 million people who die of cancer every year.

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‘Challenging’ for doctors

“In China alone an estimated 500,000 patient life-years could be saved through harmonisation of trial requirements that have delayed patient access to treatment,” former Australian prime minister Kevin Rudd, co-chair of the Bloomberg cancer coalition, said in a statement.

Mary Gospodarowicz, also a member of the coalition, said that it was “challenging” as an oncologist in Canada when a drug was approved in the US but would take years to be able to prescribe it to her patients.

The study assumed that the rest of the world had the infrastructure to diagnose and treat cancer as well as the US, which is not always the case, Gospodarowicz told AFP via phone from the World Cancer Congress in Geneva on Tuesday.

But it served as an example of how “removing the barriers to drug approval would be beneficial to patients around the world,” said the former president of the Union for International Cancer Control, which is holding the congress.

The authors of the analysis called on countries to embrace Project Orbis, a US-led framework aiming to get cancer drugs trialled and approved at the same time in multiple countries.

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“The US has already made significant progress in setting up the regulatory infrastructure for cancer treatment with the Project Orbis initiative and the task ahead is to take that framework and internationalise it,” former New York mayor Michael Bloomberg said in a statement.

International

Former Trump allies call for removal, cite 25th Amendment amid Iran threats

Former allies of U.S. President Donald Trump on Tuesday called for his removal from office, arguing he is unfit to continue in the role following recent threats to “wipe out an entire civilization,” made just hours before the deadline of his ultimatum to Iran.

One of the most prominent voices was former Republican congresswoman Marjorie Taylor Greene, who invoked the 25th Amendment of the U.S. Constitution as a mechanism to remove the president from power.

“25th Amendment! Not a single bomb has fallen on the U.S. We cannot annihilate an entire civilization. This is evil and insanity,” Greene wrote on social media platform X.

Greene, once a leading figure within Trump’s political movement during his first term, broke with the president last November over disagreements on foreign policy and his handling of controversial cases.

Another former supporter, controversial commentator Alex Jones, also raised the possibility of applying the constitutional provision during his show, in a conversation with attorney Robert Barnes.

Barnes explained that invoking the 25th Amendment requires the support of two-thirds of Congress, making it a more complex process than impeachment.

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Section 4 of the amendment, ratified in 1967, establishes that the vice president, together with a majority of the cabinet, can declare the president unable to perform the duties of the office, a decision that must then be confirmed by both chambers of Congress.

The statements come amid rising international tensions and increasing domestic political pressure on the president.

International

Trump pauses strikes on Iran, extends ultimatum by two weeks

The president of the United States, Donald Trump, announced a temporary suspension of attacks against Iran for a period of two weeks, extending the ultimatum he had imposed on Tehran just hours before its deadline.

According to the president, the measure is conditional on Iran allowing the “full, immediate, and secure” reopening of the Strait of Hormuz. Trump stated that the decision would involve a reciprocal ceasefire between both parties.

The announcement was made through a message on his social media platform, where he emphasized that the pause in military actions is intended to create space for de-escalation in the region.

He also noted that the decision followed a conversation with the prime minister of Pakistan, Shehbaz Sharif, who requested a two-week extension of the ultimatum.

The move comes amid heightened global tensions, marked by escalating threats and concerns over the potential impact of the conflict on key international energy trade routes.

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International

WHO worker killed as Israeli forces fire on Gaza medical convoy

An employee of the World Health Organization (WHO) was killed on Monday in Gaza Strip after Israeli forces opened fire on a medical convoy transporting patients for evacuation, according to witnesses and official accounts.

The Israel Defense Forces (IDF) said the vehicle approached troops in a “threatening manner,” alleging that the driver accelerated toward soldiers despite warning shots. “The troops fired warning shots. The vehicle continued advancing, and additional fire was directed at it,” the military said in a statement.

The army also claimed the vehicle lacked clear markings and was therefore treated as a potential threat.

However, survivors disputed that account. Raed Aslan, a passenger in the convoy, told reporters in Khan Younis that the vehicles were clearly marked with WHO insignia. “The vehicle was clearly identified as belonging to the WHO,” he said, adding that an Israeli tank blocked the road and fired at the driver despite the route being empty.

The convoy was transporting patients to the Rafah crossing, the only exit point available for medical evacuations abroad, as Israel does not permit transfers to Jerusalem or the West Bank.

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The incident adds to a series of controversial cases involving Israeli military actions against humanitarian convoys. In April 2024, seven workers from World Central Kitchen were killed in an Israeli strike in Deir al-Balah. The military initially cited a “misidentification,” despite the vehicles being clearly marked.

Similarly, in March 2025, 15 paramedics, rescuers, and a UN worker were killed near Rafah. Israeli authorities first claimed emergency lights were off, but video evidence later contradicted that assertion.

A subsequent investigation by organizations including Forensic Architecture found that Israeli forces fired hundreds of rounds at the convoy, and that the vehicles were later destroyed and buried along with the bodies before being recovered days later.

The latest incident is likely to intensify scrutiny over the conduct of military operations in Gaza, particularly regarding the safety of humanitarian personnel and medical evacuations.