International
Cancer drug cooperation could save 1.5 mn lives a year: researchers
AFP
Around 1.5 million lives could be saved every year if the world worked together to more swiftly approve new cancer drugs, researchers said Tuesday.
The figure was based on how long it took two recent cancer drugs to be approved across the world after they were given the green light by the United States.
Pembrolizumab, an effective treatment for most lung cancers, was approved by the US Food and Drug Administration (FDA) in 2016.
More than 600,000 years of patients’ lives could have been saved if Brazil, Canada, China, India, Japan and the European Union had approved the drug at the same time, according to an analysis published in the Harvard Business Review, which is not peer-reviewed.
The authors, including US oncologist Bobby Daly, also looked at enzalutamide, which is used to treat prostate cancer.
Enzalutamide was approved by the FDA in 2012, but was not authorised in China for another seven years, partly due to a requirement for separate trials to be carried out there.
The analysis by members of the Bloomberg New Economy International Cancer Coalition found that 284,000 years of patient lives could have been saved if other countries had approved the drug alongside the FDA.
Extrapolating out from their findings, the researchers estimated that if each of the approximately seven cancer drugs approved by the FDA a year were authorised worldwide, it would reduce the number of cancer-related deaths by 10-20 percent.
That represents roughly 1.5 million of the around 10 million people who die of cancer every year.
‘Challenging’ for doctors
“In China alone an estimated 500,000 patient life-years could be saved through harmonisation of trial requirements that have delayed patient access to treatment,” former Australian prime minister Kevin Rudd, co-chair of the Bloomberg cancer coalition, said in a statement.
Mary Gospodarowicz, also a member of the coalition, said that it was “challenging” as an oncologist in Canada when a drug was approved in the US but would take years to be able to prescribe it to her patients.
The study assumed that the rest of the world had the infrastructure to diagnose and treat cancer as well as the US, which is not always the case, Gospodarowicz told AFP via phone from the World Cancer Congress in Geneva on Tuesday.
But it served as an example of how “removing the barriers to drug approval would be beneficial to patients around the world,” said the former president of the Union for International Cancer Control, which is holding the congress.
The authors of the analysis called on countries to embrace Project Orbis, a US-led framework aiming to get cancer drugs trialled and approved at the same time in multiple countries.
“The US has already made significant progress in setting up the regulatory infrastructure for cancer treatment with the Project Orbis initiative and the task ahead is to take that framework and internationalise it,” former New York mayor Michael Bloomberg said in a statement.
International
Russia and US to Meet in Istanbul for Diplomatic Talks on April 10
The Kremlin confirmed today a forthcoming meeting with the United States to discuss the normalization of diplomatic relations, which will take place in Istanbul.
“Our participation will be through the Ministry of Foreign Affairs,” said Dmitry Peskov, the presidential spokesperson, during his daily telephone press conference.
Peskov was responding to a question about who would represent Russia in the new round of negotiations, which is supposedly scheduled for April 10.
Subsequently, the Ministry of Foreign Affairs confirmed that the delegations will be led by the Russian ambassador to the U.S., Alexandr Darchiev, and the U.S. Deputy Secretary of State, Sonata Coulter.
These are the same negotiators who met in late February in Istanbul, where the expert-level negotiation format was the same, according to the source.
Russian Foreign Minister Sergei Lavrov had said a few days ago that the next meeting would be held in the Turkish city, though he did not confirm a date.
Lavrov, who participated in only one of these meetings, clarified that the upcoming discussions would address the issues still dividing Moscow and Washington diplomatically, referring to the operations of both countries’ embassies.
The Kremlin asserted that Washington has not yet responded to Russia’s security concerns, preventing a ceasefire declaration on land, sea, and air.
Meanwhile, Trump expressed discontent with Russia’s recent attacks, including one last week that killed 20 people in Krivi Rig, the hometown of Ukrainian President Volodymyr Zelensky.
So far, Russia has rejected a cessation of hostilities and only declared a 30-day ceasefire on March 18 against attacks on energy infrastructure, which was extended by Kyiv a week later.
International
Transgender Student Arrested at Florida Capitol for Using Women’s Restroom Under New State Law
A transgender student was arrested at the Florida Capitol for using a women’s restroom, in violation of a 2023 state law that restricts the use of restrooms in government buildings based on the sex assigned at birth.
According to the American Civil Liberties Union (ACLU), this is the first known arrest for violations of transgender bathroom restrictions in the United States.
Before entering the women’s restroom in March, Marcy Rheintgen warned Capitol officers in Tallahassee, Florida’s capital, that she would be violating the law.
Rheintgen was detained and faces a misdemeanor charge of trespassing, which could carry up to 60 days in jail.
The 20-year-old’s hearing, which has reignited the national debate on transgender rights and the enforcement of similar laws in other states, is scheduled for next May.
“Marcy Rheintgen’s arrest is not about security. It’s about cruelty, humiliation, and the deliberate erosion of human dignity,” stated Nadine Smith, executive director of Equality Florida.
International
Maduro Announces Economic Emergency Decree Amid Growing Tensions with the U.S.
Nicolás Maduro, who swore in for a third term after his disputed reelection in Venezuela, announced on Monday that he will sign a decree for an economic emergency, following a proposal from Executive Vice President Delcy Rodríguez due to the “delicate moments” and “uncertainty the world is experiencing.”
“Tomorrow I will sign the constitutional economic emergency decree to protect and defend Venezuela’s economy, and I will explain it,” the Chavista leader stated in his weekly program ‘Con Maduro +.’
Maduro recalled that he has used this measure in previous years and explained that this decree allows him to assume “special, constitutional, extraordinary powers” for what he considered “the defense of the Venezuelan economy in its push, in its development.”
In the television segment, the vice president handed Maduro the document with the proposal for him to take the “reins of the economy” to “protect national industry, guarantee the provision of essential goods and services for the population, and ensure that the national economic life continues its course.”
Venezuela is facing a 15% tariff increase from the U.S., in addition to other measures such as a 25% additional tariff on buyers of Venezuelan oil or gas and the termination of licenses for oil companies to operate in the Caribbean nation, such as the U.S. company Chevron and the Spanish company Repsol.
Last Friday, Maduro assured that Venezuela would be “the first country in the world to overcome the tariffs and the trade war declared by (U.S. President, Donald) Trump against the world.”
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