International

Cancer drug cooperation could save 1.5 mn lives a year: researchers

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AFP

Around 1.5 million lives could be saved every year if the world worked together to more swiftly approve new cancer drugs, researchers said Tuesday.

The figure was based on how long it took two recent cancer drugs to be approved across the world after they were given the green light by the United States.

Pembrolizumab, an effective treatment for most lung cancers, was approved by the US Food and Drug Administration (FDA) in 2016.

More than 600,000 years of patients’ lives could have been saved if Brazil, Canada, China, India, Japan and the European Union had approved the drug at the same time, according to an analysis published in the Harvard Business Review, which is not peer-reviewed.

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The authors, including US oncologist Bobby Daly, also looked at enzalutamide, which is used to treat prostate cancer.

Enzalutamide was approved by the FDA in 2012, but was not authorised in China for another seven years, partly due to a requirement for separate trials to be carried out there.

The analysis by members of the Bloomberg New Economy International Cancer Coalition found that 284,000 years of patient lives could have been saved if other countries had approved the drug alongside the FDA.

Extrapolating out from their findings, the researchers estimated that if each of the approximately seven cancer drugs approved by the FDA a year were authorised worldwide, it would reduce the number of cancer-related deaths by 10-20 percent.

That represents roughly 1.5 million of the around 10 million people who die of cancer every year.

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‘Challenging’ for doctors

“In China alone an estimated 500,000 patient life-years could be saved through harmonisation of trial requirements that have delayed patient access to treatment,” former Australian prime minister Kevin Rudd, co-chair of the Bloomberg cancer coalition, said in a statement.

Mary Gospodarowicz, also a member of the coalition, said that it was “challenging” as an oncologist in Canada when a drug was approved in the US but would take years to be able to prescribe it to her patients.

The study assumed that the rest of the world had the infrastructure to diagnose and treat cancer as well as the US, which is not always the case, Gospodarowicz told AFP via phone from the World Cancer Congress in Geneva on Tuesday.

But it served as an example of how “removing the barriers to drug approval would be beneficial to patients around the world,” said the former president of the Union for International Cancer Control, which is holding the congress.

The authors of the analysis called on countries to embrace Project Orbis, a US-led framework aiming to get cancer drugs trialled and approved at the same time in multiple countries.

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“The US has already made significant progress in setting up the regulatory infrastructure for cancer treatment with the Project Orbis initiative and the task ahead is to take that framework and internationalise it,” former New York mayor Michael Bloomberg said in a statement.

International

Hiroshima survivor who embraced Obama dies at 88

The emotional embrace between Barack Obama and Hiroshima survivor Mori—who was eight years old when the United States dropped the atomic bomb in 1945—resonated around the world.

According to Asahi Shimbun and other local media, Mori died on Saturday at a hospital in Hiroshima.

Mori, known for his research on the fate of American prisoners of war in Hiroshima, was thrown into a river by the force of the explosion on August 6, 1945, during the atomic bombing of the city.

In a past interview with AFP, ahead of his meeting with Obama at the Hiroshima Peace Memorial in 2016, Mori recalled the chaos and desperation that followed the blast.

He described how, after emerging from the water, he encountered injured civilians seeking help amid the devastation, an experience that stayed with him throughout his life.

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In 2016, Obama became the first sitting U.S. president to visit Hiroshima, where he paid tribute to the victims of the first atomic bomb used in warfare. During the visit, Mori was visibly moved as he met the president, sharing a brief but powerful moment that symbolized remembrance and reconciliation.

The bombing of Hiroshima resulted in the deaths of approximately 140,000 people, including those who succumbed to radiation exposure in the aftermath.

Three days later, a second atomic bomb was dropped on Nagasaki, killing an estimated 74,000 people and contributing to the end of World War II.

International

Colombia seeks ‘total suffocation’ of armed groups with regional support

Colombia is advancing a strategy aimed at the “total suffocation” of illegal armed groups, seeking to corner them in border regions with the support of Ecuador and Venezuela, Defense Minister Pedro Sánchez said in an interview with AFP.

According to the minister, coordinated pressure from neighboring countries—backed by United States—aims to dismantle criminal networks that use cross-border routes to traffic Colombian cocaine toward North America and Europe.

For decades, armed groups involved in Colombia’s internal conflict have relied on border territories as strategic rear bases to evade military operations and maintain logistical support.

However, Sánchez said that dynamic is beginning to change.

“We expect a total suffocation between both nations so they have no spaces where they can live or feel safe […] to close off any room they might have,” he stated during the interview in Bogotá, less than five months before the end of President Gustavo Petro’s term.

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Regional developments have reinforced this strategy. Following the capture of Nicolás Maduro in a U.S. military operation, Washington has increased its influence in Caracas, where interim leader Delcy Rodríguez has implemented a renewed anti-narcotics policy.

Meanwhile, in Ecuador, President Daniel Noboa—a key U.S. ally in the region—has launched a two-week security plan under strict curfews to combat criminal gangs, with U.S. support.

Sánchez argued that these combined efforts leave illegal organizations with fewer escape routes and operational spaces, effectively placing them in a “dead end.”

International

Two killed in shooting at restaurant near Frankfurt Airport

Two people were shot dead early Tuesday at a restaurant in Raunheim, near Frankfurt Airport, according to local police.

Preliminary findings indicate that an armed individual entered the establishment at around 03:45 local time (02:45 GMT) and opened fire on the victims, who died at the scene from their injuries.

The suspect fled and remains at large, while the motive behind the shooting is still unclear, German media reported. Authorities have launched a large-scale search operation.