International
Cancer drug cooperation could save 1.5 mn lives a year: researchers
AFP
Around 1.5 million lives could be saved every year if the world worked together to more swiftly approve new cancer drugs, researchers said Tuesday.
The figure was based on how long it took two recent cancer drugs to be approved across the world after they were given the green light by the United States.
Pembrolizumab, an effective treatment for most lung cancers, was approved by the US Food and Drug Administration (FDA) in 2016.
More than 600,000 years of patients’ lives could have been saved if Brazil, Canada, China, India, Japan and the European Union had approved the drug at the same time, according to an analysis published in the Harvard Business Review, which is not peer-reviewed.
The authors, including US oncologist Bobby Daly, also looked at enzalutamide, which is used to treat prostate cancer.
Enzalutamide was approved by the FDA in 2012, but was not authorised in China for another seven years, partly due to a requirement for separate trials to be carried out there.
The analysis by members of the Bloomberg New Economy International Cancer Coalition found that 284,000 years of patient lives could have been saved if other countries had approved the drug alongside the FDA.
Extrapolating out from their findings, the researchers estimated that if each of the approximately seven cancer drugs approved by the FDA a year were authorised worldwide, it would reduce the number of cancer-related deaths by 10-20 percent.
That represents roughly 1.5 million of the around 10 million people who die of cancer every year.
‘Challenging’ for doctors
“In China alone an estimated 500,000 patient life-years could be saved through harmonisation of trial requirements that have delayed patient access to treatment,” former Australian prime minister Kevin Rudd, co-chair of the Bloomberg cancer coalition, said in a statement.
Mary Gospodarowicz, also a member of the coalition, said that it was “challenging” as an oncologist in Canada when a drug was approved in the US but would take years to be able to prescribe it to her patients.
The study assumed that the rest of the world had the infrastructure to diagnose and treat cancer as well as the US, which is not always the case, Gospodarowicz told AFP via phone from the World Cancer Congress in Geneva on Tuesday.
But it served as an example of how “removing the barriers to drug approval would be beneficial to patients around the world,” said the former president of the Union for International Cancer Control, which is holding the congress.
The authors of the analysis called on countries to embrace Project Orbis, a US-led framework aiming to get cancer drugs trialled and approved at the same time in multiple countries.
“The US has already made significant progress in setting up the regulatory infrastructure for cancer treatment with the Project Orbis initiative and the task ahead is to take that framework and internationalise it,” former New York mayor Michael Bloomberg said in a statement.
International
Bogotá and Quito Seek Dialogue After Tariffs and Power Cut Escalate Tensions
Bogotá and Quito will hold an emergency bilateral summit next week amid recent developments that have strained relations between the two countries.
Tensions escalated this week after Ecuadorian President Daniel Noboa unexpectedly announced a 30% tariff on Colombian imports. Colombia responded with a reciprocal measure, imposing the same tariff on around 20 Ecuadorian products and suspending electricity exports to Ecuador.
Aware that electricity imports are critical to easing Ecuador’s recent energy crises, Quito further imposed a 30% tariff on the transportation of Colombian oil through its territory.
However, recent statements from the Ecuadorian government suggest that dialogue between the two sides has intensified in recent hours. Ecuador’s Minister of Foreign Affairs, Gabriela Sommerfeld, confirmed that active conversations are under way.
In Colombia, segments of the business sector have welcomed the prospect of negotiations. The National Business Council (Consejo Gremial Nacional, CGN), for instance, urged both governments to restore commercial relations, warning that the dispute “puts jobs and regional economic stability at risk.”
International
Trump-Era Defense Plan Prioritizes Border Security and Scales Back Global Commitments
The U.S. military will prioritize the defense of the homeland and the deterrence of China, while providing more limited support to its allies and elevating Latin America as a key focus of its agenda, according to a Pentagon strategic document released on Friday.
The 2026 National Defense Strategy (NDS) represents a significant shift from previous Pentagon policies, both in its emphasis on allies assuming greater responsibility with reduced backing from Washington and in its more moderate tone toward traditional adversaries such as China and Russia.
“As U.S. forces focus on defending the homeland and the Indo-Pacific, allies and partners elsewhere will assume primary responsibility for their own defense, with crucial but more limited support from U.S. forces,” the document states.
The previous defense strategy, published during President Joe Biden’s administration, described China as Washington’s most consequential challenge and characterized Russia as an “acute threat.”
The new strategy, however, calls for maintaining “respectful relations” with Beijing and makes no reference to Taiwan, the democratically governed island claimed by China and allied with the United States. It also describes the threat posed by Russia as “persistent but manageable,” particularly affecting NATO’s eastern members.
While both the Biden-era strategy and the Trump administration’s approach emphasize the importance of defending U.S. territory, they differ significantly in their assessment of the challenges facing the country.
The Trump administration’s NDS sharply criticizes the previous government for neglecting border security, arguing that this failure led to an “influx of illegal immigrants” and widespread narcotics trafficking.
International
Guatemala considers sending high-risk gang members to military prisons
Amid the escalating crisis in Guatemala’s prison system, the government is considering transferring high-risk gang members to military-run detention facilities, a move that analysts say could help address overcrowding and the lack of control in civilian prisons.
The debate has gained urgency following the killing of ten police officers by gang members, reportedly in retaliation after the government refused to meet demands made by Aldo Dupie Ochoa, alias “El Lobo,” leader of the Barrio 18 gang, which authorities identified as responsible for the attack.
Guatemala’s Minister of Defense, Henry David Sáenz, told local media that the possibility of relocating high-danger inmates to military brigades has not been formally discussed. However, he noted that the practice is not new to the Armed Forces and said it is something that “was already being done.”
One example is the detention center located within the Mariscal Zavala Military Brigade, in Zone 17 of Guatemala City, where several inmates are held under military supervision. The facility also houses high-profile detainees, including former official Eduardo Masaya, who faces corruption charges.
In 2015, a ministerial agreement authorized the establishment of the Zone Seventeen Detention Center within the brigade, with a maximum capacity of 114 inmates in Area A and 21 in Area B. The agreement specified that the facility would be used exclusively for civilians or military personnel considered at risk of assassination.
Additionally, since 2010, a prison has operated within the Matamoros Barracks in Zone 1 of Guatemala City, holding dangerous or high-profile inmates. However, media outlets have described these military detention centers as “VIP prisons,” particularly for former government officials such as ex-president Otto Pérez Molina.
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