International
Cancer drug cooperation could save 1.5 mn lives a year: researchers
AFP
Around 1.5 million lives could be saved every year if the world worked together to more swiftly approve new cancer drugs, researchers said Tuesday.
The figure was based on how long it took two recent cancer drugs to be approved across the world after they were given the green light by the United States.
Pembrolizumab, an effective treatment for most lung cancers, was approved by the US Food and Drug Administration (FDA) in 2016.
More than 600,000 years of patients’ lives could have been saved if Brazil, Canada, China, India, Japan and the European Union had approved the drug at the same time, according to an analysis published in the Harvard Business Review, which is not peer-reviewed.
The authors, including US oncologist Bobby Daly, also looked at enzalutamide, which is used to treat prostate cancer.
Enzalutamide was approved by the FDA in 2012, but was not authorised in China for another seven years, partly due to a requirement for separate trials to be carried out there.
The analysis by members of the Bloomberg New Economy International Cancer Coalition found that 284,000 years of patient lives could have been saved if other countries had approved the drug alongside the FDA.
Extrapolating out from their findings, the researchers estimated that if each of the approximately seven cancer drugs approved by the FDA a year were authorised worldwide, it would reduce the number of cancer-related deaths by 10-20 percent.
That represents roughly 1.5 million of the around 10 million people who die of cancer every year.
‘Challenging’ for doctors
“In China alone an estimated 500,000 patient life-years could be saved through harmonisation of trial requirements that have delayed patient access to treatment,” former Australian prime minister Kevin Rudd, co-chair of the Bloomberg cancer coalition, said in a statement.
Mary Gospodarowicz, also a member of the coalition, said that it was “challenging” as an oncologist in Canada when a drug was approved in the US but would take years to be able to prescribe it to her patients.
The study assumed that the rest of the world had the infrastructure to diagnose and treat cancer as well as the US, which is not always the case, Gospodarowicz told AFP via phone from the World Cancer Congress in Geneva on Tuesday.
But it served as an example of how “removing the barriers to drug approval would be beneficial to patients around the world,” said the former president of the Union for International Cancer Control, which is holding the congress.
The authors of the analysis called on countries to embrace Project Orbis, a US-led framework aiming to get cancer drugs trialled and approved at the same time in multiple countries.
“The US has already made significant progress in setting up the regulatory infrastructure for cancer treatment with the Project Orbis initiative and the task ahead is to take that framework and internationalise it,” former New York mayor Michael Bloomberg said in a statement.
International
Trump says GOP ‘learned a lot’ after democratic election wins
U.S. President Donald Trump said that he and the Republican Party “learned a lot” from the Democratic victories in Tuesday’s state and local elections. He also compared Democrats to “kamikaze pilots” over the ongoing budget standoff.
Speaking at an event with Republican senators on Wednesday, Trump described the results as an unexpected setback.
“These were very Democratic areas, but I don’t think it was good for Republicans. In fact, I don’t think it was good for anyone. But we had an interesting night and we learned a lot,” he said during remarks broadcast by the White House.
Trump agreed with pollsters that two key factors led to Republican losses in New York’s mayoral race and the gubernatorial contests in New Jersey and Virginia.
International
Bolivia’s Jeanine Áñez freed after Supreme Court annuls her conviction
Former Bolivian interim president Jeanine Áñez was released from a women’s prison in La Paz on Thursday, where she had spent more than four and a half years for an alleged coup, after her conviction was annulled, AFP journalists confirmed.
Dozens of supporters and family members gathered outside the facility to celebrate her release. Áñez left the prison waving a Bolivian flag around 15:00 GMT.
“It is comforting to see that justice will once again prevail in Bolivia. She was the only woman who took on the role with bravery and courage,” said Lizeth Maure, a 46-year-old nurse who had come to show her support.
Áñez, a 58-year-old lawyer and conservative politician, governed Bolivia for nearly a year until November 2020, when she handed power to leftist leader Luis Arce.
She was arrested in 2021 and sentenced the following year to 10 years in prison for “resolutions contrary to the Constitution,” accused of illegally assuming the presidency after Evo Morales resigned in 2019 amid social unrest.
Her sentence was overturned on Wednesday by the Supreme Court of Justice, Bolivia’s highest judicial authority.
The court ruled that Áñez should have been subjected to a “trial of responsibilities” before Congress— a constitutional process reserved for sitting presidents, vice presidents, ministers, and top judges — rather than prosecuted in an ordinary criminal court.
As she was welcomed by relatives and supporters upon release, Áñez declared:
“I feel the satisfaction of having fulfilled my duty to my country, of never having bowed down. And I will never regret having served Bolivia when it needed me.”
International
Peru declares Mexico’s president Persona Non Grata over political asylum dispute
Peru’s Congress declared Mexican President Claudia Sheinbaum persona non grata on Thursday, accusing her of “unacceptable interference in internal affairs” after granting political asylum to former Peruvian Prime Minister Betssy Chávez.
The motion, introduced by right-wing parties, passed with 63 votes in favor, 33 against, and two abstentions. Lawmakers argue that Sheinbaum has maintained a hostile stance toward Peru since taking office.
Peru severed diplomatic relations with Mexico on Monday following the asylum decision. Chávez, who is facing charges for her alleged involvement in former President Pedro Castillo’s failed coup attempt in December 2022, remains under protection at the Mexican embassy residence in Lima.
Following the diplomatic break, interim President José Jerí said on X that Mexico’s chargé d’affaires in Peru, Karla Ornela, has been notified by the foreign ministry that she must leave the country within a strict deadline.
The Mexican government condemned Lima’s decision as “excessive and disproportionate,” asserting that offering asylum to Chávez is a legitimate act grounded in international law and does not constitute interference in Peru’s domestic matters.
Trump says GOP ‘learned a lot’ after democratic election wins
Bolivia’s Jeanine Áñez freed after Supreme Court annuls her conviction
Peru declares Mexico’s president Persona Non Grata over political asylum dispute
Tec de Monterrey honors one of its students for his contribution to nanotechnology in medicine
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