International
Cancer drug cooperation could save 1.5 mn lives a year: researchers
AFP
Around 1.5 million lives could be saved every year if the world worked together to more swiftly approve new cancer drugs, researchers said Tuesday.
The figure was based on how long it took two recent cancer drugs to be approved across the world after they were given the green light by the United States.
Pembrolizumab, an effective treatment for most lung cancers, was approved by the US Food and Drug Administration (FDA) in 2016.
More than 600,000 years of patients’ lives could have been saved if Brazil, Canada, China, India, Japan and the European Union had approved the drug at the same time, according to an analysis published in the Harvard Business Review, which is not peer-reviewed.
The authors, including US oncologist Bobby Daly, also looked at enzalutamide, which is used to treat prostate cancer.
Enzalutamide was approved by the FDA in 2012, but was not authorised in China for another seven years, partly due to a requirement for separate trials to be carried out there.
The analysis by members of the Bloomberg New Economy International Cancer Coalition found that 284,000 years of patient lives could have been saved if other countries had approved the drug alongside the FDA.
Extrapolating out from their findings, the researchers estimated that if each of the approximately seven cancer drugs approved by the FDA a year were authorised worldwide, it would reduce the number of cancer-related deaths by 10-20 percent.
That represents roughly 1.5 million of the around 10 million people who die of cancer every year.
‘Challenging’ for doctors
“In China alone an estimated 500,000 patient life-years could be saved through harmonisation of trial requirements that have delayed patient access to treatment,” former Australian prime minister Kevin Rudd, co-chair of the Bloomberg cancer coalition, said in a statement.
Mary Gospodarowicz, also a member of the coalition, said that it was “challenging” as an oncologist in Canada when a drug was approved in the US but would take years to be able to prescribe it to her patients.
The study assumed that the rest of the world had the infrastructure to diagnose and treat cancer as well as the US, which is not always the case, Gospodarowicz told AFP via phone from the World Cancer Congress in Geneva on Tuesday.
But it served as an example of how “removing the barriers to drug approval would be beneficial to patients around the world,” said the former president of the Union for International Cancer Control, which is holding the congress.
The authors of the analysis called on countries to embrace Project Orbis, a US-led framework aiming to get cancer drugs trialled and approved at the same time in multiple countries.
“The US has already made significant progress in setting up the regulatory infrastructure for cancer treatment with the Project Orbis initiative and the task ahead is to take that framework and internationalise it,” former New York mayor Michael Bloomberg said in a statement.
International
Singer seriously injured after knife attack in Tokyo’s Akasaka District
A woman in her forties was stabbed on Sunday by a man in Tokyo’s busy Akasaka district, leaving her with serious injuries, according to local media reports.
At around 10:25 a.m. (local time), police received an emergency call reporting that a woman was bleeding after being attacked with a knife by a man wearing a black hood in the basement of a building in Akasaka, police sources told Kyodo News.
The woman sustained severe injuries to her abdomen and hand but was conscious when she was transported to a hospital, Tokyo Metropolitan Police said, adding that the suspected assailant fled the scene with what appeared to be a knife.
The victim, believed to be a singer, was reportedly attacked while waiting alone outside a live music club where she was scheduled to perform.
Police stated that they are searching for the suspect and noted that the woman did not know him.
International
Ombudsman confirms deaths of six minors in bombing targeting FARC dissidents
Colombia’s Ombudsman’s Office reported on Saturday the deaths of six minors who had been recruited by guerrilla groups, killed during the deadliest airstrike ordered by President Gustavo Petro in an Amazonian region in the south of the country.
Amid pre-election criticism and pressure from the United States demanding stronger action against drug trafficking, Petro has intensified military operations against armed groups. Over the past week, a series of bombings have left 28 people dead.
The minors were killed in an airstrike announced on Tuesday against a camp belonging to dissident factions of the now-defunct FARC guerrilla in the department of Guaviare, resulting in 19 deaths—the largest operation of its kind under Petro’s administration.
“This is all deeply regrettable; it is war in its most painful and inhumane expression, harming the most vulnerable—minors recruited due to lack of protection and now turned into military targets,” said Ombudswoman Iris Marín in an audio message sent to the press, confirming the deaths of six minors without providing their ages.
Marín held the guerrilla group led by the country’s most-wanted man, alias Iván Mordisco, responsible for recruiting the children.
However, she also stressed that “the military forces must take every feasible precaution to protect children,” in accordance with international principles that require “careful evaluation of the means and methods of warfare to avoid disproportionate or unnecessary harm.”
International
Colombia reaches $4.5 billion deal to acquire 17 Gripen Fighter Jets from Saab
The Colombian government has finalized a negotiation agreement with the Swedish company Saab for the purchase of 17 SAP-39 Gripen fighter jets, valued at more than $4.5 billion, according to local media reports.
Colombian outlets indicated that payments are scheduled to begin in 2026, starting with an initial installment of 100 billion Colombian pesos. However, the aircraft will be delivered between 2027 and 2032, when the final jet is expected to arrive in Colombia.
This new contract represents the second-largest public purchase made by Colombia so far this century, surpassed only by the investment in the Bogotá metro system, local media noted.
The agreement is expected to be officially signed during the ceremony commemorating the 216th anniversary of the Colombian Aerospace Force, to be held in Cali on November 14 of this year.
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