International

Cancer drug cooperation could save 1.5 mn lives a year: researchers

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AFP

Around 1.5 million lives could be saved every year if the world worked together to more swiftly approve new cancer drugs, researchers said Tuesday.

The figure was based on how long it took two recent cancer drugs to be approved across the world after they were given the green light by the United States.

Pembrolizumab, an effective treatment for most lung cancers, was approved by the US Food and Drug Administration (FDA) in 2016.

More than 600,000 years of patients’ lives could have been saved if Brazil, Canada, China, India, Japan and the European Union had approved the drug at the same time, according to an analysis published in the Harvard Business Review, which is not peer-reviewed.

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The authors, including US oncologist Bobby Daly, also looked at enzalutamide, which is used to treat prostate cancer.

Enzalutamide was approved by the FDA in 2012, but was not authorised in China for another seven years, partly due to a requirement for separate trials to be carried out there.

The analysis by members of the Bloomberg New Economy International Cancer Coalition found that 284,000 years of patient lives could have been saved if other countries had approved the drug alongside the FDA.

Extrapolating out from their findings, the researchers estimated that if each of the approximately seven cancer drugs approved by the FDA a year were authorised worldwide, it would reduce the number of cancer-related deaths by 10-20 percent.

That represents roughly 1.5 million of the around 10 million people who die of cancer every year.

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‘Challenging’ for doctors

“In China alone an estimated 500,000 patient life-years could be saved through harmonisation of trial requirements that have delayed patient access to treatment,” former Australian prime minister Kevin Rudd, co-chair of the Bloomberg cancer coalition, said in a statement.

Mary Gospodarowicz, also a member of the coalition, said that it was “challenging” as an oncologist in Canada when a drug was approved in the US but would take years to be able to prescribe it to her patients.

The study assumed that the rest of the world had the infrastructure to diagnose and treat cancer as well as the US, which is not always the case, Gospodarowicz told AFP via phone from the World Cancer Congress in Geneva on Tuesday.

But it served as an example of how “removing the barriers to drug approval would be beneficial to patients around the world,” said the former president of the Union for International Cancer Control, which is holding the congress.

The authors of the analysis called on countries to embrace Project Orbis, a US-led framework aiming to get cancer drugs trialled and approved at the same time in multiple countries.

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“The US has already made significant progress in setting up the regulatory infrastructure for cancer treatment with the Project Orbis initiative and the task ahead is to take that framework and internationalise it,” former New York mayor Michael Bloomberg said in a statement.

International

IEA warns Middle East conflict could spark worst energy crisis in decades

The ongoing conflict in the Middle East could trigger the worst energy crisis in decades, warned Fatih Birol, head of the International Energy Agency (IEA), who described the situation as “very serious.”

Speaking at the National Press Club in Canberra, Birol compared the current scenario to the oil crises of the 1970s, noting that during those events the world lost around five million barrels of oil per day in each crisis.

“Today, we have lost 11 million barrels per day—more than the two major oil shocks combined,” he said.

The Turkish economist referred to the conflict that began on February 28, following attacks by the United States and Israel against Iran, which have significantly disrupted global energy markets and driven oil prices higher.

Birol warned that the global economy is facing a “very, very serious threat” and expressed hope that the crisis will be resolved soon.

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“No country will be immune to the effects of this crisis if it continues in this direction. Global efforts are urgently needed,” he emphasized.

International

Colombian Air Force Hercules plane crashes during takeoff with troops onboard

A Lockheed C-130 Hercules operated by the Colombian Air Force was involved in a “tragic accident” while taking off from Puerto Leguízamo, in the Putumayo department of southern Colombia, as it was transporting troops, Defense Minister Pedro Sánchez reported on Monday.

The minister stated on social media that the exact number of victims and the causes of the crash have not yet been determined. He also extended his condolences to the families affected and urged the public to avoid speculation until official information is confirmed.

“This is a deeply painful event for the country. Our prayers are with the victims and their families,” Sánchez said, adding that emergency protocols have been activated and an investigation is underway.

Meanwhile, President Gustavo Petro expressed hope that there would be no fatalities in what he described as a “horrific accident that should not have happened.”

Petro also highlighted ongoing efforts to modernize the country’s air fleet and reiterated the need to acquire new helicopters and transport aircraft to strengthen military mobility, particularly in remote regions.

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According to local media reports, approximately 110 soldiers were on board the aircraft. So far, at least 20 injured military personnel have been rescued.

International

Paris prosecutors alert U.S. over alleged deepfake strategy linked to Elon Musk

The Paris Prosecutor’s Office said on Saturday that it had alerted authorities in the United States over suspicions that tech entrepreneur Elon Musk may have encouraged the spread of sexualized deepfake content on the social platform X to artificially boost the company’s valuation.

According to prosecutors, the controversy surrounding explicit AI-generated videos—reportedly linked to Grok, the platform’s artificial intelligence system—may have been deliberately triggered to increase the market value of X and X AI.

The office added that the alleged strategy could be tied to the planned June 2026 public listing of a new entity formed through the merger of SpaceX and X AI.

French authorities said they contacted the U.S. Department of Justice as well as legal representatives at the U.S. Securities and Exchange Commission (SEC) earlier this week to share their concerns.

Responding on X in French to a report about the case, Musk referred to French prosecutors using an offensive term.

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When contacted, X’s legal representative in France did not immediately comment.

Grok, the platform’s AI system, has its own account on X, allowing users to interact with it or request content generation. For a period, users were able to tag the bot in posts to generate or edit images, a feature that may have facilitated the spread of such material.