International

Cancer drug cooperation could save 1.5 mn lives a year: researchers

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AFP

Around 1.5 million lives could be saved every year if the world worked together to more swiftly approve new cancer drugs, researchers said Tuesday.

The figure was based on how long it took two recent cancer drugs to be approved across the world after they were given the green light by the United States.

Pembrolizumab, an effective treatment for most lung cancers, was approved by the US Food and Drug Administration (FDA) in 2016.

More than 600,000 years of patients’ lives could have been saved if Brazil, Canada, China, India, Japan and the European Union had approved the drug at the same time, according to an analysis published in the Harvard Business Review, which is not peer-reviewed.

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The authors, including US oncologist Bobby Daly, also looked at enzalutamide, which is used to treat prostate cancer.

Enzalutamide was approved by the FDA in 2012, but was not authorised in China for another seven years, partly due to a requirement for separate trials to be carried out there.

The analysis by members of the Bloomberg New Economy International Cancer Coalition found that 284,000 years of patient lives could have been saved if other countries had approved the drug alongside the FDA.

Extrapolating out from their findings, the researchers estimated that if each of the approximately seven cancer drugs approved by the FDA a year were authorised worldwide, it would reduce the number of cancer-related deaths by 10-20 percent.

That represents roughly 1.5 million of the around 10 million people who die of cancer every year.

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‘Challenging’ for doctors

“In China alone an estimated 500,000 patient life-years could be saved through harmonisation of trial requirements that have delayed patient access to treatment,” former Australian prime minister Kevin Rudd, co-chair of the Bloomberg cancer coalition, said in a statement.

Mary Gospodarowicz, also a member of the coalition, said that it was “challenging” as an oncologist in Canada when a drug was approved in the US but would take years to be able to prescribe it to her patients.

The study assumed that the rest of the world had the infrastructure to diagnose and treat cancer as well as the US, which is not always the case, Gospodarowicz told AFP via phone from the World Cancer Congress in Geneva on Tuesday.

But it served as an example of how “removing the barriers to drug approval would be beneficial to patients around the world,” said the former president of the Union for International Cancer Control, which is holding the congress.

The authors of the analysis called on countries to embrace Project Orbis, a US-led framework aiming to get cancer drugs trialled and approved at the same time in multiple countries.

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“The US has already made significant progress in setting up the regulatory infrastructure for cancer treatment with the Project Orbis initiative and the task ahead is to take that framework and internationalise it,” former New York mayor Michael Bloomberg said in a statement.

International

Exclusive Tucson Neighborhood Shaken by Disappearance of Savannah Guthrie’s Mother

The disappearance of Nancy Guthrie, mother of well-known U.S. journalist Savannah Guthrie, has shaken the exclusive Catalina Foothills neighborhood in northern Tucson, Arizona. For the past eleven days, the area has become the focus of an intensive investigation and constant media attention.

The 84-year-old woman was last seen on January 31, when she returned home after a family dinner. Since then, authorities have released few details about the suspected abduction.

“It is worrying that an elderly person could be the victim of a crime like this in her own home; we are a community of retirees,” Mario Ruiz, a resident who lives near the property, told EFE.

He explained that neighbors in the area tend to respect each other’s privacy, and many homes do not even have fences, surrounded only by the desert landscape about 110 kilometers from the Mexican border.

Support for the family is visible in an improvised altar set up outside Guthrie’s house. Flowers, candles and a message written on a stone — “Please pray, bring her home” — reflect the concern felt by the community.

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During a visit to Catalina Foothills on Wednesday, a strong presence of FBI agents could be seen patrolling nearby roads and neighborhoods in search of any clue that might help locate Guthrie.

Officers have been checking bushes, trash containers and surrounding areas near the residence, which is located in one of Tucson’s most exclusive districts, close to shopping centers, private golf courses and resorts.

International

Over 50 Civil Groups Urge House to Impeach DHS Secretary Kristi Noem

More than 50 civil society organizations, including Latino collectives and migrant advocacy groups, on Tuesday urged the U.S. House of Representatives to open impeachment proceedings against Homeland Security Secretary Kristi Noem, whom they accuse of leading a migration policy that is “violent, reckless, and contrary to the Constitution.”

The request was submitted through a letter sent to House Speaker Mike Johnson and other legislative leaders. In the document, the organizations argue that Noem has encouraged repressive practices that have left multiple victims and have “intentionally undermined the mission of the Department of Homeland Security (DHS).”

Among the signatories are Voto Latino, Freedom for Immigrants (FFI), Hispanic Federation, UnidosUS, and the Latino Victory Project. The groups emphasized that at least 187 lawmakers already support the impeachment initiative introduced in January by Representative Robin Kelly for alleged “high crimes and misdemeanors.”

The accusations include the alleged obstruction of congressional access to migrant detention centers and the excessive use of force, with at least 14 people shot since July 2025. They also cite three documented deaths, including those of U.S. citizens Renee Good and Alex Pretti.

The organizations further criticized the detention of migrant children, pointing to the case of five-year-old Liam Conejo Ramos, arrested in Minnesota last month, which sparked nationwide controversy.

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They also denounced that operations carried out by Immigration and Customs Enforcement (ICE) have resulted in due process violations, unlawful detentions of Indigenous citizens, and disregard for court orders. According to the signatories, Noem has “dismantled” civil rights protections within the DHS and has shown a lack of understanding of constitutional principles such as habeas corpus.

Central America

Guatemala to Phase Out Longstanding Medical Cooperation Agreement with Cuba

Guatemala’s government announced on Tuesday that it will end this year a cooperation agreement with Cuba that has brought doctors from the Caribbean nation to work in the Central American country.

Guatemala’s Health Ministry told EFE that the program, which has been in place for nearly three decades, will be phased out progressively throughout 2026.

According to the same source, there are currently 412 Cubans in Guatemala under the agreement, including 333 physicians.

Cuban medical brigades assigned to Guatemala have traditionally been deployed to various regions of the country to provide primary health care to local communities.

“The decision follows a technical assessment aimed at strengthening the sustainability of the national workforce and consolidating the public health system’s own capacities,” the Guatemalan ministry said.

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Earlier this week, lawmaker Sonia Gutiérrez, from the left-wing Winaq party, warned that the move “could be an inhumane act that threatens the health and lives of the country’s most vulnerable populations,” given the historic importance of Cuban doctors in providing medical care.

For that reason, the legislator summoned Health Ministry authorities to Congress, as permitted by law, to provide further details about the decision.

Former human rights ombudsman Jordán Rodas Andrade also weighed in on social media, recalling that “for 27 years Cuban doctors have been the backbone of health care in Guatemala’s most neglected areas,” and stressing that “ending this agreement is an act of ingratitude that leaves the most vulnerable unprotected.”

President Bernardo Arévalo’s government told EFE that, in order to guarantee continued care, it will implement a gradual replacement plan that includes hiring national personnel.