International

Cancer drug cooperation could save 1.5 mn lives a year: researchers

Ilustrative image

AFP

Around 1.5 million lives could be saved every year if the world worked together to more swiftly approve new cancer drugs, researchers said Tuesday.

The figure was based on how long it took two recent cancer drugs to be approved across the world after they were given the green light by the United States.

Pembrolizumab, an effective treatment for most lung cancers, was approved by the US Food and Drug Administration (FDA) in 2016.

More than 600,000 years of patients’ lives could have been saved if Brazil, Canada, China, India, Japan and the European Union had approved the drug at the same time, according to an analysis published in the Harvard Business Review, which is not peer-reviewed.

20250501_mh_noexigencia_dui_728x90

The authors, including US oncologist Bobby Daly, also looked at enzalutamide, which is used to treat prostate cancer.

Enzalutamide was approved by the FDA in 2012, but was not authorised in China for another seven years, partly due to a requirement for separate trials to be carried out there.

The analysis by members of the Bloomberg New Economy International Cancer Coalition found that 284,000 years of patient lives could have been saved if other countries had approved the drug alongside the FDA.

Extrapolating out from their findings, the researchers estimated that if each of the approximately seven cancer drugs approved by the FDA a year were authorised worldwide, it would reduce the number of cancer-related deaths by 10-20 percent.

That represents roughly 1.5 million of the around 10 million people who die of cancer every year.

20250501_mh_noexigencia_dui_728x90

‘Challenging’ for doctors

“In China alone an estimated 500,000 patient life-years could be saved through harmonisation of trial requirements that have delayed patient access to treatment,” former Australian prime minister Kevin Rudd, co-chair of the Bloomberg cancer coalition, said in a statement.

Mary Gospodarowicz, also a member of the coalition, said that it was “challenging” as an oncologist in Canada when a drug was approved in the US but would take years to be able to prescribe it to her patients.

The study assumed that the rest of the world had the infrastructure to diagnose and treat cancer as well as the US, which is not always the case, Gospodarowicz told AFP via phone from the World Cancer Congress in Geneva on Tuesday.

But it served as an example of how “removing the barriers to drug approval would be beneficial to patients around the world,” said the former president of the Union for International Cancer Control, which is holding the congress.

The authors of the analysis called on countries to embrace Project Orbis, a US-led framework aiming to get cancer drugs trialled and approved at the same time in multiple countries.

20250501_mh_noexigencia_dui_728x90

“The US has already made significant progress in setting up the regulatory infrastructure for cancer treatment with the Project Orbis initiative and the task ahead is to take that framework and internationalise it,” former New York mayor Michael Bloomberg said in a statement.

International

Winter Storm Fern Leaves 30 Dead and Over One Million Without Power Across the U.S.

The massive winter storm Fern, bringing polar temperatures, battered large portions of the United States for a third consecutive day on Monday, leaving at least 30 people dead, more than one million households without electricity, and thousands of flights grounded.

In the Great Lakes region, residents awoke to extreme cold, with temperatures dropping below -20°C. Forecasts indicate that conditions are expected to worsen in the coming days as an Arctic air mass moves south, particularly across the northern Great Plains and other central regions, where wind chills could plunge to -45°C, temperatures capable of causing frostbite within minutes.

Across the country, heavy snowfall exceeding 30 centimeters in roughly 20 states triggered widespread power outages. According to PowerOutage.com, nearly 800,000 customers remained without electricity on Monday morning, most of them in the southern United States.

In Tennessee, where ice brought down power lines, approximately 250,000 customers were still without power. Outages also affected more than 150,000 customers in Mississippi and over 100,000 in Louisiana, as utility crews struggled to restore service amid dangerous conditions.

International

Spain approves plan to regularize up to 500,000 migrants in Historic Shift

In November 2024, Spanish Prime Minister Pedro Sánchez announced a reform of the country’s immigration regulations aimed at regularizing 300,000 migrants per year over a three-year period, in an effort to counter population aging in a country where births have fallen by 25.6% since 2014, according to official data.

Going against the trend in much of Europe, Spain’s left-wing government has now approved an exceptional migrant regularization plan that could benefit up to 500,000 people, most of them from Latin America.

The measure will allow the regularization of around “half a million people” who have been living in Spain for at least five months, arrived before December 31, 2025, and have no criminal record, Migration Minister Elma Saiz explained on public television.

The plan, approved on Tuesday by the Council of Ministers, establishes that applications will be processed between April and June 30, enabling beneficiaries to work in any sector and anywhere in the country, Saiz said.

“Today is a historic day for our country. We are strengthening a migration model based on human rights, integration, and one that is compatible with economic growth and social cohesion,” the minister later stated at a press conference.

20250501_mh_noexigencia_dui_728x90

The socialist government of Pedro Sánchez stands out within the European Union for its migration policy, contrasting with the tightening of immigration measures across much of the bloc amid pressure from far-right movements.

Central America

Honduras swears in conservative president Asfura after disputed election

Conservative politician Nasry Asfura assumed the presidency of Honduras on Tuesday with an agenda closely aligned with the United States, a shift that could strain the country’s relationship with China as he seeks to confront the economic and security challenges facing the poorest and most violent nation in Central America.

Asfura’s rise to power, backed by U.S. President Donald Trump, marks the end of four years of left-wing rule and secures Trump another regional ally amid the advance of conservative governments in Chile, Bolivia, Peru, and Argentina.

The 67-year-old former mayor and construction businessman was sworn in during an austere ceremony at the National Congress, following a tightly contested election marred by opposition allegations of fraud and Trump’s threat to cut U.S. aid if his preferred candidate did not prevail.

Grateful for Washington’s support, Asfura—who is of Palestinian descent—traveled to the United States to meet with Secretary of State Marco Rubio, before visiting Israeli Prime Minister Benjamin Netanyahu.

“We need to strengthen relations with our most important trading partner,” Asfura said after being declared the winner of the November 30 election by a narrow margin, following a tense vote count that lasted just over three weeks.