International
Cancer drug cooperation could save 1.5 mn lives a year: researchers
AFP
Around 1.5 million lives could be saved every year if the world worked together to more swiftly approve new cancer drugs, researchers said Tuesday.
The figure was based on how long it took two recent cancer drugs to be approved across the world after they were given the green light by the United States.
Pembrolizumab, an effective treatment for most lung cancers, was approved by the US Food and Drug Administration (FDA) in 2016.
More than 600,000 years of patients’ lives could have been saved if Brazil, Canada, China, India, Japan and the European Union had approved the drug at the same time, according to an analysis published in the Harvard Business Review, which is not peer-reviewed.
The authors, including US oncologist Bobby Daly, also looked at enzalutamide, which is used to treat prostate cancer.
Enzalutamide was approved by the FDA in 2012, but was not authorised in China for another seven years, partly due to a requirement for separate trials to be carried out there.
The analysis by members of the Bloomberg New Economy International Cancer Coalition found that 284,000 years of patient lives could have been saved if other countries had approved the drug alongside the FDA.
Extrapolating out from their findings, the researchers estimated that if each of the approximately seven cancer drugs approved by the FDA a year were authorised worldwide, it would reduce the number of cancer-related deaths by 10-20 percent.
That represents roughly 1.5 million of the around 10 million people who die of cancer every year.
‘Challenging’ for doctors
“In China alone an estimated 500,000 patient life-years could be saved through harmonisation of trial requirements that have delayed patient access to treatment,” former Australian prime minister Kevin Rudd, co-chair of the Bloomberg cancer coalition, said in a statement.
Mary Gospodarowicz, also a member of the coalition, said that it was “challenging” as an oncologist in Canada when a drug was approved in the US but would take years to be able to prescribe it to her patients.
The study assumed that the rest of the world had the infrastructure to diagnose and treat cancer as well as the US, which is not always the case, Gospodarowicz told AFP via phone from the World Cancer Congress in Geneva on Tuesday.
But it served as an example of how “removing the barriers to drug approval would be beneficial to patients around the world,” said the former president of the Union for International Cancer Control, which is holding the congress.
The authors of the analysis called on countries to embrace Project Orbis, a US-led framework aiming to get cancer drugs trialled and approved at the same time in multiple countries.
“The US has already made significant progress in setting up the regulatory infrastructure for cancer treatment with the Project Orbis initiative and the task ahead is to take that framework and internationalise it,” former New York mayor Michael Bloomberg said in a statement.
International
Haitian authorities mobilize nationwide as gangs threaten confrontation with police
Haiti’s National Police (PNH) declared a state of maximum alert after the leader of the Viv Ansanm armed coalition, Jimmy Chérizier — known as “Barbecue” — urged the population to stay indoors amid the prospect of clashes with security forces carrying out an offensive against gang groups.
The threats came days after the PNH, the Haitian Armed Forces (FAD’H), and the Gang Suppression Force (GSF) launched a large-scale operation against the 400 Mawozo gang, which for years has controlled and kidnapped residents in Tabarre and Croix-des-Bouquets, north of the capital.
The police announced the suspension of all vacations and leave for officers “in order to mobilize all police personnel, with the goal of ensuring optimal security for the population and responding to any eventuality.” Authorities reported that operations will continue specifically in Croix-des-Bouquets, territory controlled by 400 Mawozo under the command of Lanmò Sanjou.
In recent days, security forces located and raided several hideouts used by criminal groups, managing to kill or force the retreat of gang members from strategic areas. Police Director General Vladimir Paraison visited the barracks of the units involved in the operations to express his “appreciation for the courage and commitment of the police in their relentless battles to restore order and uphold the law.”
Chérizier — for whom the United States has offered a $5 million reward — urged citizens on Sunday to remain in their homes so the gangs could confront police forces and “avoid becoming victims.”
“The time has come, Haitian people, to unite to liberate this country,” he declared in a message shared on social media.
International
U.S. House poised to approve bill requiring declassification of Epstein files
A group of lawmakers in the U.S. House of Representatives said on Tuesday that a bill requiring the Department of Justice to declassify documents related to the case of billionaire Jeffrey Epstein is expected to pass with “overwhelming” support.
Democratic Representative Ro Khanna, the sponsor of the proposal, urged the Senate not to allow delays or amendments. “I expect it to pass by an overwhelming majority in the House. I don’t want politicians playing games with this. They need to pass it in the Senate without changes,” he said from Capitol Hill, joined by Republicans Thomas Massie, Marjorie Taylor Greene, and several Epstein victims.
The vote is scheduled for Tuesday at 2:00 p.m. local time, after 218 lawmakers from both parties forced House Speaker Mike Johnson to bring the measure to the floor.
U.S. President Donald Trump, who has been criticized by Democrats for his past friendship with Epstein, stated that he would sign the bill if it passes both chambers of Congress. His support came after a shift in his position, following his name appearing in leaked documents.
Representative Marjorie Taylor Greene, a frequent ally of the president, publicly confronted Trump in recent days over the issue. Standing alongside several Epstein victims, she defended her backing of the bill despite Trump calling her a “traitor.” “These women have fought the most horrible battle that no woman should ever have to fight (…) even against the president of the United States,” she said.
Taylor Greene added that the “real test” will be whether the Department of Justice complies with releasing the documents once the bill is enacted. “Or everything will remain sealed under the pretext of ongoing investigations,” she warned.
Haley Robson, one of the victims, also spoke during the press event. “I’m traumatized, I’m not stupid,” she said firmly, arguing that attempts by certain sectors to delay the process have caused tremendous emotional harm. “This is not political. This is America. This is the land of freedom,” she stated.
International
Five mexicans detained in North Carolina immigration raids, Sheinbaum confirms
Mexico’s President Claudia Sheinbaum confirmed on Tuesday that five Mexican citizens were detained during immigration raids carried out over the weekend in North Carolina, United States. She indicated that the federal government is already providing assistance and consular protection to those affected.
“There are five Mexican nationals in custody, and the Consulate General of Mexico in Raleigh is in communication with them to provide assistance and consular protection,” Sheinbaum said during her morning press conference. She reiterated that protecting Mexicans abroad is a priority for her administration, and that the Foreign Ministry will closely follow the case.
The announcement comes after an operation known as Charlotte’s Web, conducted by U.S. immigration authorities in the city of Charlotte, the state’s financial hub. The raid resulted in at least 81 arrests, including Mexican and Honduran nationals.
The operation focused on targeting “illegal aliens with criminal records,” according to the Department of Homeland Security (DHS), which cited more than 1,400 outstanding arrest warrants that have not been executed due to so-called sanctuary policies in certain cities.
However, North Carolina Governor Josh Stein stated that “the vast majority” of those detained do not have criminal records. Stein urged the public to document immigration operations and protest peacefully, as already witnessed in cities such as Los Angeles, Chicago, and Portland.
One of the most widely shared cases online is that of Willy Aceituno, a U.S. citizen born in Honduras, who reported being violently detained by immigration agents despite having valid documentation. DHS responded by accusing him of “erratic behavior” and claiming that an agent was injured after a civilian crashed their vehicle during the operation.
Haitian authorities mobilize nationwide as gangs threaten confrontation with police
U.S. House poised to approve bill requiring declassification of Epstein files
Five mexicans detained in North Carolina immigration raids, Sheinbaum confirms
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