International

Cancer drug cooperation could save 1.5 mn lives a year: researchers

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AFP

Around 1.5 million lives could be saved every year if the world worked together to more swiftly approve new cancer drugs, researchers said Tuesday.

The figure was based on how long it took two recent cancer drugs to be approved across the world after they were given the green light by the United States.

Pembrolizumab, an effective treatment for most lung cancers, was approved by the US Food and Drug Administration (FDA) in 2016.

More than 600,000 years of patients’ lives could have been saved if Brazil, Canada, China, India, Japan and the European Union had approved the drug at the same time, according to an analysis published in the Harvard Business Review, which is not peer-reviewed.

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The authors, including US oncologist Bobby Daly, also looked at enzalutamide, which is used to treat prostate cancer.

Enzalutamide was approved by the FDA in 2012, but was not authorised in China for another seven years, partly due to a requirement for separate trials to be carried out there.

The analysis by members of the Bloomberg New Economy International Cancer Coalition found that 284,000 years of patient lives could have been saved if other countries had approved the drug alongside the FDA.

Extrapolating out from their findings, the researchers estimated that if each of the approximately seven cancer drugs approved by the FDA a year were authorised worldwide, it would reduce the number of cancer-related deaths by 10-20 percent.

That represents roughly 1.5 million of the around 10 million people who die of cancer every year.

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‘Challenging’ for doctors

“In China alone an estimated 500,000 patient life-years could be saved through harmonisation of trial requirements that have delayed patient access to treatment,” former Australian prime minister Kevin Rudd, co-chair of the Bloomberg cancer coalition, said in a statement.

Mary Gospodarowicz, also a member of the coalition, said that it was “challenging” as an oncologist in Canada when a drug was approved in the US but would take years to be able to prescribe it to her patients.

The study assumed that the rest of the world had the infrastructure to diagnose and treat cancer as well as the US, which is not always the case, Gospodarowicz told AFP via phone from the World Cancer Congress in Geneva on Tuesday.

But it served as an example of how “removing the barriers to drug approval would be beneficial to patients around the world,” said the former president of the Union for International Cancer Control, which is holding the congress.

The authors of the analysis called on countries to embrace Project Orbis, a US-led framework aiming to get cancer drugs trialled and approved at the same time in multiple countries.

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“The US has already made significant progress in setting up the regulatory infrastructure for cancer treatment with the Project Orbis initiative and the task ahead is to take that framework and internationalise it,” former New York mayor Michael Bloomberg said in a statement.

International

Paris prosecutors alert U.S. over alleged deepfake strategy linked to Elon Musk

The Paris Prosecutor’s Office said on Saturday that it had alerted authorities in the United States over suspicions that tech entrepreneur Elon Musk may have encouraged the spread of sexualized deepfake content on the social platform X to artificially boost the company’s valuation.

According to prosecutors, the controversy surrounding explicit AI-generated videos—reportedly linked to Grok, the platform’s artificial intelligence system—may have been deliberately triggered to increase the market value of X and X AI.

The office added that the alleged strategy could be tied to the planned June 2026 public listing of a new entity formed through the merger of SpaceX and X AI.

French authorities said they contacted the U.S. Department of Justice as well as legal representatives at the U.S. Securities and Exchange Commission (SEC) earlier this week to share their concerns.

Responding on X in French to a report about the case, Musk referred to French prosecutors using an offensive term.

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When contacted, X’s legal representative in France did not immediately comment.

Grok, the platform’s AI system, has its own account on X, allowing users to interact with it or request content generation. For a period, users were able to tag the bot in posts to generate or edit images, a feature that may have facilitated the spread of such material.

International

Netanyahu vows to target Iran’s leadership after missile strikes in southern Israel

Israeli Prime Minister Benjamin Netanyahu vowed on Sunday to target Iran’s leadership directly, escalating rhetoric amid ongoing hostilities between Israel and Iran.

Speaking during a visit to the southern city of Arad, which was struck by an Iranian missile a day earlier, Netanyahu said Israel would intensify its response against Tehran.

“We are going after the regime. We are going after the Islamic Revolutionary Guard Corps, that gang of criminals,” he told reporters while standing among the debris left by the தாக்க.

He added that Israel intends to strike “personally” at Iran’s leadership, as well as its facilities and economic assets.

In addition to Arad, Iranian missiles also hit the city of Dimona on Saturday. The area is widely believed to host Israel’s undeclared nuclear facilities. The strike caused significant damage following a direct impact.

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Netanyahu also visited Dimona, where he urged residents to strictly follow military instructions and seek shelter whenever warning sirens are activated.

“The entire nation is a front line, and the home front is also a front line. And when we are on the front line, we follow these instructions,” he said.

International

US panel backs Trump-themed coin amid controversy

The United States Department of the Treasury confirmed to AFP that the Commission of Fine Arts approved the design of a new collectible coin featuring Donald Trump, with members of the commission appointed by the current administration.

According to the proposal, the coin will feature an image of Trump standing with clenched fists over a desk on the obverse, while the reverse will display an eagle, a traditional symbol of the United States.

The sale price of the collectible has not yet been disclosed, although the United States Mint typically offers similar items for more than $1,000.

“There is no more iconic portrait for the front of these coins than that of our president Donald Trump,” U.S. Treasurer Brandon Beach said in a statement sent to AFP. He added that two additional coins — a $1 piece and a one-ounce gold coin — are also under consideration.

However, the Citizens Coinage Advisory Committee (CCAC), another body responsible for reviewing new coin proposals, declined to discuss the Trump design in late February.

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“Only nations governed by kings or dictators place the image of a sitting leader on their currency,” said Donald Scarinciat the time. “No country in the world has minted coins featuring a democratically elected leader during their term in office,” he added.

When contacted by AFP, the Treasury Department did not immediately respond to requests for further comment.