International
Cancer drug cooperation could save 1.5 mn lives a year: researchers
AFP
Around 1.5 million lives could be saved every year if the world worked together to more swiftly approve new cancer drugs, researchers said Tuesday.
The figure was based on how long it took two recent cancer drugs to be approved across the world after they were given the green light by the United States.
Pembrolizumab, an effective treatment for most lung cancers, was approved by the US Food and Drug Administration (FDA) in 2016.
More than 600,000 years of patients’ lives could have been saved if Brazil, Canada, China, India, Japan and the European Union had approved the drug at the same time, according to an analysis published in the Harvard Business Review, which is not peer-reviewed.
The authors, including US oncologist Bobby Daly, also looked at enzalutamide, which is used to treat prostate cancer.
Enzalutamide was approved by the FDA in 2012, but was not authorised in China for another seven years, partly due to a requirement for separate trials to be carried out there.
The analysis by members of the Bloomberg New Economy International Cancer Coalition found that 284,000 years of patient lives could have been saved if other countries had approved the drug alongside the FDA.
Extrapolating out from their findings, the researchers estimated that if each of the approximately seven cancer drugs approved by the FDA a year were authorised worldwide, it would reduce the number of cancer-related deaths by 10-20 percent.
That represents roughly 1.5 million of the around 10 million people who die of cancer every year.
‘Challenging’ for doctors
“In China alone an estimated 500,000 patient life-years could be saved through harmonisation of trial requirements that have delayed patient access to treatment,” former Australian prime minister Kevin Rudd, co-chair of the Bloomberg cancer coalition, said in a statement.
Mary Gospodarowicz, also a member of the coalition, said that it was “challenging” as an oncologist in Canada when a drug was approved in the US but would take years to be able to prescribe it to her patients.
The study assumed that the rest of the world had the infrastructure to diagnose and treat cancer as well as the US, which is not always the case, Gospodarowicz told AFP via phone from the World Cancer Congress in Geneva on Tuesday.
But it served as an example of how “removing the barriers to drug approval would be beneficial to patients around the world,” said the former president of the Union for International Cancer Control, which is holding the congress.
The authors of the analysis called on countries to embrace Project Orbis, a US-led framework aiming to get cancer drugs trialled and approved at the same time in multiple countries.
“The US has already made significant progress in setting up the regulatory infrastructure for cancer treatment with the Project Orbis initiative and the task ahead is to take that framework and internationalise it,” former New York mayor Michael Bloomberg said in a statement.
International
FBI Warns of Possible Iranian Drone Attack on U.S. West Coast
The Federal Bureau of Investigation (FBI) has warned police departments in California about a possible Iranian plan to carry out a drone attack against the west coast of the United States, according to a report published Wednesday by ABC News.
The warning was issued through a memorandum sent to agencies participating in a Joint Terrorism Task Force, outlining the possibility of a surprise attack involving unmanned aerial vehicles launched from a vessel off the U.S. coastline.
According to the document, intelligence suggested that in early February 2026 Iran may have considered an attack against unspecified targets in California if the United States carried out airstrikes on Iranian territory.
However, the memo also noted that authorities lack additional details about the timing, method, specific targets, or individuals responsible for the alleged plan.
Reports cited by U.S. media indicate that the alert coincided with the start of a military offensive by the administration of Donald Trump against the Iran, a development that has heightened tensions across the Middle East.
Law enforcement sources with counterterrorism experience told the Los Angeles Times that the warning is part of a routine precautionary advisory based on information from the U.S. Coast Guard.
The sources emphasized that there is no credible indication of an imminent attack and no evidence that Iran currently has the capability to successfully carry out such an operation.
California is home to the largest Iranian community in the United States. According to the Migration Policy Institute, more than half of Iranian immigrants in the country lived in the state in 2019, including around 140,000 people in Los Angeles County alone.
The city also hosts a neighborhood widely known as “Tehrangeles,” where a large Iranian community began settling in the 1960s and continued to grow following the Iranian Revolution.
International
Trump Says Iran Is Welcome at 2026 World Cup but Warns of Security Concerns
The President of the United States, Donald Trump, said Thursday that the national football team of Iran is “welcome” to participate in the 2026 World Cup, although he suggested it might be safer for the team not to take part in the tournament.
“The Iranian national soccer team is welcome at the World Cup, but I really don’t think it’s appropriate for them to be there, for their own safety,” Trump wrote on his social media platform Truth Social.
His comments came a day after Iran’s sports minister, Ahman Donyamali, said that there are currently no conditions for the country to participate in the tournament following the killing of Iran’s Supreme Leader, Ali Khamenei, during a military offensive launched on February 28 by Israel and the United States.
“After the corrupt government killed our leader, there are no conditions that allow us to take part in the World Cup,” the Iranian official said. He added that the country has faced two wars in the past eight or nine months, resulting in thousands of civilian deaths, making participation in the tournament unlikely.
On Tuesday, the president of FIFA, Gianni Infantino, met with Trump at the White House.
Following the meeting, Infantino said that Trump reiterated that Iran’s national team would be allowed to compete in the FIFA World Cup 2026.
“We discussed the current situation in Iran and the fact that the Iranian team has qualified to participate in the FIFA World Cup 2026. During the conversation, President Trump reiterated that the Iranian team is, of course, welcome to compete in the tournament in the United States,” Infantino wrote on Instagram.
International
Iran issues threat to Trump as conflict escalates over Strait of Hormuz
The head of Iran’s Supreme National Security Council, Ali Larijani, threatened U.S. President Donald Trump on Tuesday, warning him to “beware of being eliminated.”
The Republican president had warned on Monday that he would strike Iran “very hard” if the Islamic Republic blocked oil shipments through the Strait of Hormuz, which has effectively been closed since the war began eleven days ago.
“Iran is not afraid of your empty threats. Others more powerful than you tried to destroy the Iranian nation and failed. Beware that you are not eliminated,” Larijani wrote on X.
Earlier, Iran’s Revolutionary Guards — the ideological military force of the Islamic Republic — also said their forces would move to block oil exports from the Gulf.
Meanwhile, Israeli Prime Minister Benjamin Netanyahu said Israel’s military offensive against Iran is far from over.
“Our aspiration is that the Iranian people free themselves from the yoke of tyranny; ultimately, that depends on them. But there is no doubt that with the measures taken so far we are breaking their bones, and we are not finished yet,” Netanyahu said in a statement.
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