International

Cancer drug cooperation could save 1.5 mn lives a year: researchers

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AFP

Around 1.5 million lives could be saved every year if the world worked together to more swiftly approve new cancer drugs, researchers said Tuesday.

The figure was based on how long it took two recent cancer drugs to be approved across the world after they were given the green light by the United States.

Pembrolizumab, an effective treatment for most lung cancers, was approved by the US Food and Drug Administration (FDA) in 2016.

More than 600,000 years of patients’ lives could have been saved if Brazil, Canada, China, India, Japan and the European Union had approved the drug at the same time, according to an analysis published in the Harvard Business Review, which is not peer-reviewed.

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The authors, including US oncologist Bobby Daly, also looked at enzalutamide, which is used to treat prostate cancer.

Enzalutamide was approved by the FDA in 2012, but was not authorised in China for another seven years, partly due to a requirement for separate trials to be carried out there.

The analysis by members of the Bloomberg New Economy International Cancer Coalition found that 284,000 years of patient lives could have been saved if other countries had approved the drug alongside the FDA.

Extrapolating out from their findings, the researchers estimated that if each of the approximately seven cancer drugs approved by the FDA a year were authorised worldwide, it would reduce the number of cancer-related deaths by 10-20 percent.

That represents roughly 1.5 million of the around 10 million people who die of cancer every year.

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‘Challenging’ for doctors

“In China alone an estimated 500,000 patient life-years could be saved through harmonisation of trial requirements that have delayed patient access to treatment,” former Australian prime minister Kevin Rudd, co-chair of the Bloomberg cancer coalition, said in a statement.

Mary Gospodarowicz, also a member of the coalition, said that it was “challenging” as an oncologist in Canada when a drug was approved in the US but would take years to be able to prescribe it to her patients.

The study assumed that the rest of the world had the infrastructure to diagnose and treat cancer as well as the US, which is not always the case, Gospodarowicz told AFP via phone from the World Cancer Congress in Geneva on Tuesday.

But it served as an example of how “removing the barriers to drug approval would be beneficial to patients around the world,” said the former president of the Union for International Cancer Control, which is holding the congress.

The authors of the analysis called on countries to embrace Project Orbis, a US-led framework aiming to get cancer drugs trialled and approved at the same time in multiple countries.

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“The US has already made significant progress in setting up the regulatory infrastructure for cancer treatment with the Project Orbis initiative and the task ahead is to take that framework and internationalise it,” former New York mayor Michael Bloomberg said in a statement.

International

Trump orders U.S. control of Strait of Hormuz after failed Iran talks

U.S. President Donald Trump announced on Sunday that the United States will take control of the Strait of Hormuz“effective immediately,” following the collapse of negotiations with Iran held in Islamabad.

In a post on Truth Social, Trump said he had ordered the U.S. Navy to block vessels attempting to enter or exit the strategic waterway, a key route for global energy trade.

“The meeting went well, agreement was reached on most points, but the only really important one — nuclear weapons — was not approved,” Trump said, referring to the talks with Iranian representatives.

The president also stated that he had instructed authorities to intercept ships in international waters that had paid tolls to Iran to transit the strait, calling such payments “illegal.” He further accused Tehran of hindering an agreement by deploying mines in the area, describing the move as “international extortion.”

Trump added that the United States will undertake efforts to clear mines from the strait and expressed confidence that a future agreement ensuring free navigation could eventually be reached.

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The announcement came after Vice President JD Vance and special envoys Steve Witkoff and Jared Kushner briefed the president on the outcome of the negotiations, considered the highest-level contacts between the two countries since the 1979 Islamic Revolution.

While Trump acknowledged that enough progress had been made to maintain a temporary truce, he criticized Iran for remaining unwilling to abandon its nuclear ambitions, calling its position “very inflexible” on the central issue.

International

Child Found Malnourished in Van in France; Father Admits Confinement

French gendarmes discovered a child in a van in Hagenbach, in northeastern France, after a neighbor reported hearing what she described as “childlike noises” coming from the parked vehicle.

After unlocking the van, officers found the boy lying in a fetal position, unclothed and covered with a blanket, surrounded by garbage and near human waste, according to a statement from the Mulhouse prosecutor, Nicolas Heitz.

Authorities said the child appeared pale and severely malnourished. Due to prolonged confinement in a seated position, he was no longer able to walk. He was immediately taken to a hospital in Mulhouse for medical care.

The boy’s father, who lived with his partner and two daughters aged 10 and 12, admitted to keeping the child confined and depriving him of proper care.

According to the prosecutor, the man said he placed the child in the van in November 2024, claiming he wanted to “protect him” because his partner intended to have the boy admitted to a psychiatric facility.

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The suspect also stated that he allowed the child out of the vehicle in May 2025 and permitted him to enter the family apartment around mid-year, when the rest of the family was on vacation.

The man’s partner—who is not the child’s mother—also faces charges, including failure to report abuse. However, she has denied all accusations.

International

Europe Faces Jet Fuel Shortage Risk Amid Hormuz Disruption

The Airports Council International Europe has warned of a potential “systemic shortage” of jet fuel if maritime traffic through the Strait of Hormuz is not restored within the next three weeks, according to a letter reviewed by AFP on Friday.

In the document, addressed to the European Commission and first reported by the Financial Times, the European airport lobby stated that a “systemic jet fuel shortage will become a reality” in the European Union unless stable and significant transit through the strait resumes soon.

The association, which represents around 600 airports across 50 countries, called on Brussels to implement “urgent monitoring of fuel availability and supply” over the next six months.

Jet fuel prices have surged amid the conflict in the Middle East and the ongoing disruption in the Strait of Hormuz, a critical chokepoint for global energy transport.

The conflict escalated on February 28 following joint U.S. and Israeli airstrikes against Iran.

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In response, Tehran imposed several countermeasures, including blocking maritime traffic through the strait, a route through which roughly 20% of the world’s oil, jet fuel, and gas supply passes.