International

Cancer drug cooperation could save 1.5 mn lives a year: researchers

Ilustrative image

AFP

Around 1.5 million lives could be saved every year if the world worked together to more swiftly approve new cancer drugs, researchers said Tuesday.

The figure was based on how long it took two recent cancer drugs to be approved across the world after they were given the green light by the United States.

Pembrolizumab, an effective treatment for most lung cancers, was approved by the US Food and Drug Administration (FDA) in 2016.

More than 600,000 years of patients’ lives could have been saved if Brazil, Canada, China, India, Japan and the European Union had approved the drug at the same time, according to an analysis published in the Harvard Business Review, which is not peer-reviewed.

20250501_mh_noexigencia_dui_728x90

The authors, including US oncologist Bobby Daly, also looked at enzalutamide, which is used to treat prostate cancer.

Enzalutamide was approved by the FDA in 2012, but was not authorised in China for another seven years, partly due to a requirement for separate trials to be carried out there.

The analysis by members of the Bloomberg New Economy International Cancer Coalition found that 284,000 years of patient lives could have been saved if other countries had approved the drug alongside the FDA.

Extrapolating out from their findings, the researchers estimated that if each of the approximately seven cancer drugs approved by the FDA a year were authorised worldwide, it would reduce the number of cancer-related deaths by 10-20 percent.

That represents roughly 1.5 million of the around 10 million people who die of cancer every year.

20250501_mh_noexigencia_dui_728x90

‘Challenging’ for doctors

“In China alone an estimated 500,000 patient life-years could be saved through harmonisation of trial requirements that have delayed patient access to treatment,” former Australian prime minister Kevin Rudd, co-chair of the Bloomberg cancer coalition, said in a statement.

Mary Gospodarowicz, also a member of the coalition, said that it was “challenging” as an oncologist in Canada when a drug was approved in the US but would take years to be able to prescribe it to her patients.

The study assumed that the rest of the world had the infrastructure to diagnose and treat cancer as well as the US, which is not always the case, Gospodarowicz told AFP via phone from the World Cancer Congress in Geneva on Tuesday.

But it served as an example of how “removing the barriers to drug approval would be beneficial to patients around the world,” said the former president of the Union for International Cancer Control, which is holding the congress.

The authors of the analysis called on countries to embrace Project Orbis, a US-led framework aiming to get cancer drugs trialled and approved at the same time in multiple countries.

20250501_mh_noexigencia_dui_728x90

“The US has already made significant progress in setting up the regulatory infrastructure for cancer treatment with the Project Orbis initiative and the task ahead is to take that framework and internationalise it,” former New York mayor Michael Bloomberg said in a statement.

International

Colombia to Send High-Level Delegation to Ecuador to Ease Trade Tensions

Colombia’s Ministry of Foreign Affairs confirmed on Friday that, at the instruction of President Gustavo Petro, a high-level delegation will travel to Ecuador in an effort to normalize bilateral relations, which have deteriorated following the imposition of reciprocal tariffs.

“In line with Colombia’s policy of good neighborliness and the spirit of cooperation and integration that guides its foreign policy,” the Foreign Ministry said in a statement, adding that the delegation will be led by Foreign Minister Rosa Villavicencio and Defense Minister Pedro Sánchez.

“Following instructions from the Presidency of the Republic, and as has been publicly reiterated, the Colombian delegation expects to reaffirm Colombia’s offer of support to the Republic of Ecuador to strengthen control over phenomena stemming from transnational organized crime,” the statement said.

The Foreign Ministry noted that the delegation will attend the meeting with a full willingness to engage in dialogue and to seek concrete solutions to the unilateral measures that have affected the longstanding relationship between the two neighboring countries.

Trade tensions between Ecuador and Colombia escalated on January 21, when Ecuadorian President Daniel Noboaimposed a 30% tariff on Colombian products, citing a lack of cooperation in anti-drug efforts. Colombia responded with similar measures and the suspension of energy exports, while Ecuador increased transportation costs for Colombian crude oil.

20250501_mh_noexigencia_dui_728x90

Business associations in both countries have warned that the dispute is harming both economies and have called on the governments to resolve their differences through dialogue.

International

Super Bowl Halftime Show Puts Bad Bunny—and Immigration Politics—Back in the Spotlight

The long-standing argument that sports and politics should not mix may be put to the test on Sunday during the Super Bowl halftime show, which will be headlined by Puerto Rican superstar Bad Bunny, a choice that has sparked backlash from segments of the U.S. right wing.

Just one week after his headline-making appearance at the Grammy Awards—where he sharply criticized the United States’ anti-immigration policies—Bad Bunny will once again take center stage on the global spotlight with his performance at the NFL final in Santa Clara, California.

Beyond the expectations surrounding the show itself, speculation has grown over whether the artist could again use the platform to protest policies associated with the administration of former President Donald Trump, in front of an audience expected to exceed 120 million viewers in the United States alone.

In fact, one of the most popular Super Bowl prop bets this year revolves around whether the Puerto Rican singer will deliver a direct message against ICE (U.S. Immigration and Customs Enforcement), similar to the one he delivered at the Grammys last Sunday.

While few expect Bad Bunny to repeat such a pointed statement, the mere speculation highlights the delicate balance the NFL must manage during the most-watched broadcast of the year.

20250501_mh_noexigencia_dui_728x90

The world’s most powerful sports league has drawn criticism from the MAGA movement since announcing in September that Bad Bunny would headline a halftime show largely performed in Spanish.

Trump himself declined to attend the matchup between the New England Patriots and the Seattle Seahawks, despite having made history last year as the first sitting U.S. president to attend a Super Bowl. He described the musical lineup—which also includes outspoken critics such as Green Day—as “a terrible choice” that would “sow hatred.” In response, his supporters have organized an alternative event dubbed the “All-American Halftime Show,” featuring like-minded artists such as Kid Rock.

International

Venezuela Debates Broad Amnesty Law Covering 27 Years of Chavismo

Venezuela’s Parliament began debating on Thursday a sweeping amnesty bill that would cover the 27 years of Chavismo in power, while explicitly excluding serious human rights violations and crimes against humanity.

The proposed legislation, titled the “Amnesty Law for Democratic Coexistence,” was introduced by interim President Delcy Rodríguez, who assumed power following the capture of Nicolás Maduro during a U.S. military operation.

The legislative session was convened for Thursday afternoon, with lawmakers holding an initial discussion focused on the general principles of the bill. This phase precedes a consultation process with civil society, after which the proposal will move to a final debate examining each article individually.

According to a draft of the bill obtained by AFP, the amnesty would apply to individuals accused of crimes such as “treason,” “terrorism,” and “incitement to hatred,” charges that were frequently brought against political prisoners over the past decades. The scope also includes offenses ranging from acts of rebellion to punishments imposed for social media posts or messages sent through private messaging services.

The bill’s explanatory text emphasizes reconciliation, stating that it seeks to move away from “vengeance, retaliation, and hatred” in favor of “opening a path toward reconciliation.”

20250501_mh_noexigencia_dui_728x90

However, the proposal explicitly excludes from its benefits crimes such as “serious human rights violations, crimes against humanity, war crimes, intentional homicide, corruption, and drug trafficking.”

These exclusions, the text notes, are based on strict compliance with the Venezuelan Constitution, which already prohibits granting amnesties or pardons for such offenses.