International

Cancer drug cooperation could save 1.5 mn lives a year: researchers

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AFP

Around 1.5 million lives could be saved every year if the world worked together to more swiftly approve new cancer drugs, researchers said Tuesday.

The figure was based on how long it took two recent cancer drugs to be approved across the world after they were given the green light by the United States.

Pembrolizumab, an effective treatment for most lung cancers, was approved by the US Food and Drug Administration (FDA) in 2016.

More than 600,000 years of patients’ lives could have been saved if Brazil, Canada, China, India, Japan and the European Union had approved the drug at the same time, according to an analysis published in the Harvard Business Review, which is not peer-reviewed.

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The authors, including US oncologist Bobby Daly, also looked at enzalutamide, which is used to treat prostate cancer.

Enzalutamide was approved by the FDA in 2012, but was not authorised in China for another seven years, partly due to a requirement for separate trials to be carried out there.

The analysis by members of the Bloomberg New Economy International Cancer Coalition found that 284,000 years of patient lives could have been saved if other countries had approved the drug alongside the FDA.

Extrapolating out from their findings, the researchers estimated that if each of the approximately seven cancer drugs approved by the FDA a year were authorised worldwide, it would reduce the number of cancer-related deaths by 10-20 percent.

That represents roughly 1.5 million of the around 10 million people who die of cancer every year.

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‘Challenging’ for doctors

“In China alone an estimated 500,000 patient life-years could be saved through harmonisation of trial requirements that have delayed patient access to treatment,” former Australian prime minister Kevin Rudd, co-chair of the Bloomberg cancer coalition, said in a statement.

Mary Gospodarowicz, also a member of the coalition, said that it was “challenging” as an oncologist in Canada when a drug was approved in the US but would take years to be able to prescribe it to her patients.

The study assumed that the rest of the world had the infrastructure to diagnose and treat cancer as well as the US, which is not always the case, Gospodarowicz told AFP via phone from the World Cancer Congress in Geneva on Tuesday.

But it served as an example of how “removing the barriers to drug approval would be beneficial to patients around the world,” said the former president of the Union for International Cancer Control, which is holding the congress.

The authors of the analysis called on countries to embrace Project Orbis, a US-led framework aiming to get cancer drugs trialled and approved at the same time in multiple countries.

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“The US has already made significant progress in setting up the regulatory infrastructure for cancer treatment with the Project Orbis initiative and the task ahead is to take that framework and internationalise it,” former New York mayor Michael Bloomberg said in a statement.

International

White House says Cuba policy unchanged despite sanctioned fuel shipment

The White House said Monday that it has not changed its policy toward Cuba, despite allowing a sanctioned Russian oil tanker to deliver fuel to the island on humanitarian grounds.

U.S. officials emphasized that the decision was made as an exception and does not signal a broader shift in policy.

The administration added that similar decisions would be evaluated on a case-by-case basis, depending on humanitarian considerations.

The clarification comes amid ongoing restrictions related to U.S. sanctions policy, which continue to limit trade and financial flows involving Cuba.

International

Spain to grant citizenship to Venezuelan opposition leader Leopoldo López

The Spanish government is expected to grant citizenship this Tuesday to Venezuelan opposition leader Leopoldo Lópezthrough an extraordinary procedure known as “carta de naturaleza.”

The decision will be approved by royal decree, an exceptional legal mechanism used in special cases that require expedited resolution due to specific circumstances.

López has been living in Madrid since 2020, after leaving Venezuela following a prolonged political and legal conflict with the government of Nicolás Maduro.

According to government sources, López currently does not have a valid Venezuelan passport and faces difficulties in having his nationality fully recognized in his home country.

As a result, he applied for Spanish citizenship via a fast-track process at the end of 2025, after previously attempting to obtain it through regular procedures.

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The Spanish government justified the move based on López’s international relevance and foreign policy considerations.

López is the leader of the Voluntad Popular party and co-founder of the World Liberty Congress, an initiative launched in 2022 alongside figures such as Garry Kasparov and Masih Alinejad.

International

ICE to remain at airports amid DHS shutdown, Homan says

The U.S. “border czar,” Tom Homan, said Sunday that agents from U.S. Immigration and Customs Enforcement (ICE) will remain deployed at airports until operations return to “100% normal,” as the shutdown of the Department of Homeland Security (DHS) continues.

“We will maintain ICE presence until airports feel they are fully back to normal operations,” Homan said during an interview on Face the Nation on CBS.

Homan justified the deployment on security grounds, noting that the measure was ordered by President Donald Trumpamid widespread absenteeism among agents of the Transportation Security Administration, who have gone without pay for over six weeks due to the DHS shutdown.

According to acting TSA administrator Ha Nguyen McNeill, at least 460 TSA agents have resigned during the shutdown, while daily absenteeism has averaged 11%, exceeding 50% at some airports.

Homan warned that if TSA staffing levels do not recover after the shutdown, ICE agents will continue filling the gap. “ICE is there to support our TSA brothers and sisters. We will remain as long as needed to ensure airport security,” he said.

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The DHS shutdown reached 44 days on Sunday, making it the longest government shutdown in U.S. history. The impasse stems from disagreements between Democrats and Republicans over ICE funding.

A recent bipartisan Senate proposal to fund DHS without including ICE failed after being blocked by House Republicans, who insist on full funding for the agency.

Amid the deadlock, Trump signed an executive order directing Homeland Security Secretary Markwayne Mullin to immediately pay TSA agents to address what he called an “emergency situation” and restore order at airports, with payments expected to begin Monday.