International

Cancer drug cooperation could save 1.5 mn lives a year: researchers

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AFP

Around 1.5 million lives could be saved every year if the world worked together to more swiftly approve new cancer drugs, researchers said Tuesday.

The figure was based on how long it took two recent cancer drugs to be approved across the world after they were given the green light by the United States.

Pembrolizumab, an effective treatment for most lung cancers, was approved by the US Food and Drug Administration (FDA) in 2016.

More than 600,000 years of patients’ lives could have been saved if Brazil, Canada, China, India, Japan and the European Union had approved the drug at the same time, according to an analysis published in the Harvard Business Review, which is not peer-reviewed.

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The authors, including US oncologist Bobby Daly, also looked at enzalutamide, which is used to treat prostate cancer.

Enzalutamide was approved by the FDA in 2012, but was not authorised in China for another seven years, partly due to a requirement for separate trials to be carried out there.

The analysis by members of the Bloomberg New Economy International Cancer Coalition found that 284,000 years of patient lives could have been saved if other countries had approved the drug alongside the FDA.

Extrapolating out from their findings, the researchers estimated that if each of the approximately seven cancer drugs approved by the FDA a year were authorised worldwide, it would reduce the number of cancer-related deaths by 10-20 percent.

That represents roughly 1.5 million of the around 10 million people who die of cancer every year.

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‘Challenging’ for doctors

“In China alone an estimated 500,000 patient life-years could be saved through harmonisation of trial requirements that have delayed patient access to treatment,” former Australian prime minister Kevin Rudd, co-chair of the Bloomberg cancer coalition, said in a statement.

Mary Gospodarowicz, also a member of the coalition, said that it was “challenging” as an oncologist in Canada when a drug was approved in the US but would take years to be able to prescribe it to her patients.

The study assumed that the rest of the world had the infrastructure to diagnose and treat cancer as well as the US, which is not always the case, Gospodarowicz told AFP via phone from the World Cancer Congress in Geneva on Tuesday.

But it served as an example of how “removing the barriers to drug approval would be beneficial to patients around the world,” said the former president of the Union for International Cancer Control, which is holding the congress.

The authors of the analysis called on countries to embrace Project Orbis, a US-led framework aiming to get cancer drugs trialled and approved at the same time in multiple countries.

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“The US has already made significant progress in setting up the regulatory infrastructure for cancer treatment with the Project Orbis initiative and the task ahead is to take that framework and internationalise it,” former New York mayor Michael Bloomberg said in a statement.

International

Child Found Malnourished in Van in France; Father Admits Confinement

French gendarmes discovered a child in a van in Hagenbach, in northeastern France, after a neighbor reported hearing what she described as “childlike noises” coming from the parked vehicle.

After unlocking the van, officers found the boy lying in a fetal position, unclothed and covered with a blanket, surrounded by garbage and near human waste, according to a statement from the Mulhouse prosecutor, Nicolas Heitz.

Authorities said the child appeared pale and severely malnourished. Due to prolonged confinement in a seated position, he was no longer able to walk. He was immediately taken to a hospital in Mulhouse for medical care.

The boy’s father, who lived with his partner and two daughters aged 10 and 12, admitted to keeping the child confined and depriving him of proper care.

According to the prosecutor, the man said he placed the child in the van in November 2024, claiming he wanted to “protect him” because his partner intended to have the boy admitted to a psychiatric facility.

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The suspect also stated that he allowed the child out of the vehicle in May 2025 and permitted him to enter the family apartment around mid-year, when the rest of the family was on vacation.

The man’s partner—who is not the child’s mother—also faces charges, including failure to report abuse. However, she has denied all accusations.

International

Europe Faces Jet Fuel Shortage Risk Amid Hormuz Disruption

The Airports Council International Europe has warned of a potential “systemic shortage” of jet fuel if maritime traffic through the Strait of Hormuz is not restored within the next three weeks, according to a letter reviewed by AFP on Friday.

In the document, addressed to the European Commission and first reported by the Financial Times, the European airport lobby stated that a “systemic jet fuel shortage will become a reality” in the European Union unless stable and significant transit through the strait resumes soon.

The association, which represents around 600 airports across 50 countries, called on Brussels to implement “urgent monitoring of fuel availability and supply” over the next six months.

Jet fuel prices have surged amid the conflict in the Middle East and the ongoing disruption in the Strait of Hormuz, a critical chokepoint for global energy transport.

The conflict escalated on February 28 following joint U.S. and Israeli airstrikes against Iran.

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In response, Tehran imposed several countermeasures, including blocking maritime traffic through the strait, a route through which roughly 20% of the world’s oil, jet fuel, and gas supply passes.

International

Artemis II crew prepares for Earth return and splashdown recovery

Astronauts from the Artemis II mission are expected to be extracted from the Orion spacecraft approximately two hours after splashdown, scheduled for 20:07 UTC this Friday (6:07 p.m. in San Salvador), according to NASA.

Following recovery, a rescue team will transport the crew by aircraft to the USS John P. Murtha. Once onboard, they will undergo medical evaluations before boarding another flight to the Johnson Space Center.

On Thursday, NASA astronauts Reid Wiseman, Victor Glover, and Christina Koch, along with Canadian astronaut Jeremy Hansen from the Canadian Space Agency, continued preparations for their return to Earth.

Their activities include stowing equipment used during the mission, securing cargo and storage compartments, and installing and adjusting crew seats to ensure all items are properly fastened. The crew will also review the latest weather updates, recovery operations status, and reentry timeline, while preparing for post-landing procedures.

At 21:53 UTC (9:53 p.m. in San Salvador), Orion’s thrusters are scheduled to perform a second trajectory correction maneuver, refining the spacecraft’s path back to Earth. During this operation, Hansen will monitor guidance, navigation, and propulsion systems.

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NASA explained that during Friday’s reentry, the service module will separate about 20 minutes before Orion reaches the upper atmosphere southeast of Hawaii. If necessary, a final trajectory adjustment will fine-tune the flight path before the capsule begins a series of roll maneuvers to safely distance itself from jettisoned components.

Just before atmospheric interface, Orion will reach a peak speed of approximately 3,800 km/h. As it descends to about 400,000 feet (around 121.9 km), communications will be interrupted for approximately six minutes due to plasma formation around the capsule during peak heating.

NASA expects the crew to experience up to 3.9 G during a nominal reentry profile. After exiting the blackout phase, the capsule will jettison its forward bay cover. Drogue parachutes will deploy at around 22,000 feet (6.7 km), followed by the three main parachutes at approximately 6,000 feet (1.8 km).

Artemis II marks NASA’s first crewed flight test of the Space Launch System (SLS) rocket and Orion spacecraft around the Moon. The mission aims to validate capabilities for deep space human exploration and lay the groundwork for future long-term scientific missions on the lunar surface.